Sex Differences in E-cig Perception: Study 1

Sex Differences in E-Cigarette Flavor Sensory Perception As It Relates to Appeal and Reinforcing Efficacy Among Adult Smokers: Study 1

The primary objective is to examine the influence of sex on sensory effects, appeal, and reinforcing value of nicotine containing e-cigs in popular flavor components; sweet and cooling.

This study looks at the effect of sex on the sensory effects of flavor components in e-cigarettes. Regular combustible tobacco users will sample 3 different flavored e-cigarettes containing nicotine in a human lab paradigm.

Inclusion Criteria:

• 21-44 years old
• Able to read/write
• Current cigarette smoking
• Recent E-cig Exposure (>/= 10 uses in past 6 mo.)
• Urine cot >200ng/ml
• Willing to abstain from nicotine/tobacco 6-8hrs prior to lab session
• Not looking to quit

Exclusion Criteria:

• Untreated chronic medical conditions
• Non-stable Rx medication
• Illicit drug use
• Pregnant, trying to become pregnant, breastfeeding
• Not fully vaccinated for Coronavirus (e.g. COVID-19)