Flavors and E-cigarette Effects in Adolescent Smokers- STUDY 1

Flavors and E-cigarette Effects in Adolescent Smokers- STUDY 1

This study is to examine if inhaled doses of menthol that produce low and high cooling effects change the appeal of e-cigarettes containing low and high doses of nicotine in adolescent smokers. The hypothesis is that the combination of nicotine and menthol, when compared with menthol or nicotine alone, will result in greater increase in liking of an e-cigarette and greater reduction in nicotine withdrawal.

Inclusion Criteria:

• Ages 18-20 years
• Able to read and write
• Cigarette smoker
• Use of e-cigarettes in the past 30 days

Exclusion Criteria:

• Seeking smoking cessation treatment
• Current/lifetime criteria for dependence on another psychoactive substance -Daily use of alcohol or marijuana or use of any other drugs including cocaine, opiates, stimulants
• Regular use of psychoactive drugs including anxiolytics, antidepressants and other psychostimulants
• Current or past history of psychosis or other psychiatric diagnosis such as major depression
• Any significant current medical condition