Developing E-liquid Product Standards (Sweet Spot Study)

Nicotine Concentration and Forms: Differential Appeal to Smokers Versus Non-Smokers

The Sweet Spot Study aims to evaluate the effect of e-liquids with nicotine varying in freebase (FB) levels and concentrations on the appeal of electronic cigarettes (ECs) in young adult EC users with minimal/no history of smoking and older adult smokers.

Inclusion criteria:

1. Young adult e-cigarette user or older adult smoker
2. Willing to abstain from all nicotine product use for 12 hours prior to the study visit
3. Read and speak English

Exclusion criteria:

1. Currently attempting to quit nicotine products
2. Currently pregnant, planning to become pregnant, or breastfeeding
3. Current or past use of tobacco products other than e-cigarettes or cigarettes
4. Self-reported diagnosis of lung disease
5. Self-reported new or unstable cardiovascular disease