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An artificial intelligence-assisted system is trained and validated by collecting nasopharyngolaryngoscopy images from patients.
To address the clinical pain points of traditional nasopharyngolaryngoscopy, such as incomplete visualization, inaccurate identification, and unclear imaging, this study will retrospectively collect nasopharyngolaryngoscopy images and baseline information (including gender and age) of patients who underwent nasopharyngolaryngoscopy at participating centers for model training and validation. Deep learning algorithms will be applied to construct the model. The final clinical performance evaluation of the model will be conducted using an independent, prospectively collected test cohort.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Model training and validation cohorts | A deep learning model is trained using the training dataset and validated with the internal validation set. |
| |
| Prospective test cohort | Patients are prospectively enrolled, nasopharyngolaryngoscopy examination videos are collected, and the video data are processed to form a prospective test dataset, which is then used for testing. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Diagnostic | Other | The deep learning model is trained using the training dataset and tested with the internal validation set. |
|
| Measure | Description | Time Frame |
|---|---|---|
| performance of lesion detection | The area under the receiver operating characteristic curve (ROC-AUC) of the model for abnormal lesion detection | Within 3 months after the completion of prospective data collection |
| performance of anatomic site recognition | The average precision (AP) of the model for recognizing nasopharyngeal and laryngeal anatomic sites | Within 3 months after the completion of prospective data collection |
| Measure | Description | Time Frame |
|---|---|---|
| Comparison of diagnostic performance between the model and physicians | Differences in sensitivity, specificity, and overall accuracy between the AI model and endoscopists with different years of experience | Within 3 months after the completion of prospective data collection |
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Inclusion Criteria:
Exclusion Criteria:
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Image data of patients who underwent nasopharyngolaryngoscopy and met the research requirements were collected from various sub-centers nationwide.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Bin Ye, MD PhD | Contact | +8615216616895 | aydyebin@126.com |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Ruijin Hospital, Shanghai Jiao Tong University School of Medicine | Recruiting | Shanghai | China |
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| ID | Term |
|---|---|
| D009303 | Nasopharyngeal Neoplasms |
| D007818 | Laryngeal Diseases |
| ID | Term |
|---|---|
| D010610 | Pharyngeal Neoplasms |
| D010039 | Otorhinolaryngologic Neoplasms |
| D006258 | Head and Neck Neoplasms |
| D009371 | Neoplasms by Site |
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| Diagnostic | Other | The prospective dataset is used for the comparative testing of the model and physicians. |
|
| D009369 | Neoplasms |
| D009302 | Nasopharyngeal Diseases |
| D010608 | Pharyngeal Diseases |
| D009057 | Stomatognathic Diseases |
| D010038 | Otorhinolaryngologic Diseases |
| D012140 | Respiratory Tract Diseases |