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The aim of this study is to investigate the effect of dual site-dual channel non-invasive brain stimulation for recovery of language and cognitive function in healthy. Simultaneous dual site-dual channel stimulation was applied by using two sets of transcranial direct current stimulation devices. All subjects will go through four conditions of transcranial direct current stimulation with for 30 minutes. Four conditions are 1) Dual stimulation: i) anodal stimulation on left inferior frontal cortex, ii) anodal stimulation on left dorsolateral prefrontal cortex. 2) IFG stimulation: anodal stimulation on left inferior frontal cortex; 3) DLPFC stimulation: anodal stimulation on left dorsolateral prefrontal cortex area. 4) sham stimulation
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Dual stimulation | Experimental | i) anodal stimulation of left inferior frontal cortex ii) anodal stimulation on left dorsolateral prefrontal cortex |
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| IFG stimulation | Active Comparator | anodal stimulation of left inferior frontal cortex |
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| DLPFC stimulation | Active Comparator | anodal stimulation on left dorsolateral prefrontal cortex |
|
| Sham stimulation | Sham Comparator | sham stimulation |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| IFG stimulation | Device | stimulating left inferior frontal cortex with transcranial direct current stimulation for 30 minutes |
|
| Measure | Description | Time Frame |
|---|---|---|
| Korean Boston naming test | measures naming ability thorough picture naming test | Baseline and after intervention (approximately 30 minutes) |
| Verbal 3 back test | measure working memory | Baseline and after intervention (approximately 30 minutes) |
| Measure | Description | Time Frame |
|---|---|---|
| Korean Color Word Stroop test | measures selective attention and executive function | Baseline and after intervention (approximately 30 minutes) |
| Controlled Oral Word Association Test | measure verbal fluency |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Samsung Medical Center | Seoul | South Korea |
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| DLPFC stimulation | Device | stimulating left dorsolateral prefrontal cortex with transcranial direct current stimulation for 30 minutes |
|
| Sham stimulation | Device | sham stimulation over both left inferior frontal cortex and dorsolateral prefrontal cortex |
|
| Baseline and after intervention (approximately 30 minutes) |