Effect of Amino Acid on Muscle Damage

Effect of Leucine-enriched Essential Amino Acid on Integrated Muscle Protein Synthesis and Muscle Recovery After Resistance Exercise

The primary objective is to determine the impact of essential amino acids on integrated muscle protein synthesis over 4 days after resistance exercise.

In addition, the secondary objective is to determine the effect of essential amino acids on satellite cell regulation and inflammatory responses during this prolonged recovery period.

Inclusion Criteria:

• Healthy, male, recreationally-active participants
• Healthy will be defined as screened by the PAR-Q+ (The Physical Activity Readiness Questionnaire for everyone; Appendix. B). Active will be defined as being in the top 20% of age specific scores on iPAQ (the International Physical Activity Questionnaire; Appendix.C).
• Participants are required not to engage in lower limb RT (resistance training) for at least 6 months prior to the study.
• Participants will be 18-35 years old.
• Participants are willing to abide by the compliance rules of this study

Exclusion Criteria:

• Female
• Inability to adhere to any of the compliance rules judged by principle investigator or medical doctor
• Self-reported regular tobacco use
• Self-reported illicit drug use (e.g. growth hormone, testosterone, etc.)
• The individual who has allergy for milk