Effects of Essential and Non-Essential Amino Acids on Post-Exercise Muscle Collagen Synthesis in Young Men

The Effects of Essential and Non-Essential Amino Acids on Post-Exercise Muscle Collagen Synthesis in Young Men: a Randomized Controlled Trial

The purpose of this study is to assess which amino acids are affecting acute muscle collagen synthesis in response to supplementation and exercise.

This is a double-blinded, randomized controlled, parallel design study, with 3 treatment groups (placebo, collagen peptide, and essential amino acid). The study will involve 3 visits: a baseline testing/familiarization session, and 2 exercise trials which will include muscle biopsies, blood draws, and the infusion of a tracer isotope in order to measure muscle protein synthesis.

Inclusion Criteria:

• Can fluently read and write in English
• Male
• 18 - 35 years

Exclusion Criteria:

• Diabetes, cardiovascular disease, or current pharmaceutical therapy
• Medical conditions impacting ability to undertake strenuous physical activity
• Lower body resistance training in the previous 6 months
• BMI > 30
• Currently smoking with cigarettes
• Allergy to any study supplements
• Currently taking any protein, amino acid, or collagen supplement
• Participate in greater than 2 hours of weekly vigorous exercise