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| Name | Class |
|---|---|
| Rousselot BVBA | INDUSTRY |
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The aim of the study is to investigate the acute and short-term effects of collagen peptides (Collagen Peptan) on muscle and connective tissue during an eccentric overload training period. Currently, all studies investigating the effects of post-exercise collagen supplementation did this in the absence of whey proteins, which are part of the standard recommendations for post-exercise recovery. The investigators will therefore investigate whether the combined intake of whey proteins and collagen peptides ensures a better recovery of exercise performance and whether it can prevent or reduce symptoms of muscle and tendon overload during a three-week eccentric overload training period (n = 22).
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Placebo | Placebo Comparator | Only whey protein will be provided |
|
| Collagen | Experimental | A mix of whey protein and collagen peptides will be provided |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| whey protein | Dietary Supplement | Daily 45g of whey protein supplementation during a three week eccentric training period |
|
| Measure | Description | Time Frame |
|---|---|---|
| Change in countermovement jump performance | Change in jump height when performing a countermovement jump, measured via a force platform | Pretest - 48 hours after the first training session (day 3 of training intervention) - Posttest (day 22 of training intervention) |
| Change in maximal isometric knee-extension force of the right leg | Change in maximal isometric knee-extension force (angle = 45°) of the right leg | Pretest - 48 hours after the first training session (day 3 of training intervention) - Posttest (day 22 of training intervention) |
| Change in anteroposterior thickness of the right patellar tendon | Change in anteroposterior thickness of the right patellar tendon | Pretest - 48 hours after the first training session (day 3 of training intervention) - Posttest (day 22 of training intervention) |
| Change in neovascularization of the right patellar tendon | Neovascularization of the right patellar tendon scored with the Modified Ohberg Score (range 0 - 4; the higher the score, the higher the degree of neovascularization). | Pretest - 48 hours after the first training session (day 3 of training intervention) - Posttest (day 22 of training intervention) |
| Measure | Description | Time Frame |
|---|---|---|
| Change in pain perception at the muscular level (VAS scale) | Change in pain perception at the muscular level of the right leg, measured via the Visual Analogue Scale (range 0 - 10; the higher the score, the higher the pain level) | Training 1 (day 1 of training intervention) - Training 2 (day 3 of training intervention) - Training 8 (day 9 of training intervention) - Training 17 (day 19 of training intervention) - Posttest (day 22 of training intervention) |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Exercise Physiology Research Group | Leuven | Vlaams-Brabant | 3001 | Belgium |
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| ID | Term |
|---|---|
| D009043 | Motor Activity |
| ID | Term |
|---|---|
| D001519 | Behavior |
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| ID | Term |
|---|---|
| D000067816 | Whey Proteins |
| ID | Term |
|---|---|
| D008894 | Milk Proteins |
| D000080224 | Animal Proteins, Dietary |
| D004044 | Dietary Proteins |
| D011506 | Proteins |
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| whey protein + collagen peptide | Dietary Supplement | Daily 15g of whey protein and 20g collagen peptide supplementation during a three week eccentric training period |
|
| Change in pain perception of the patellar tendon of the right leg (VISA-P) | Change in pain perception of the patellar tendon of the right leg, measured via the VISA-P questionnaire (range: 0 - 100; the lower the score, the higher the symptoms of patellar tendon overload) | Pretest - Training 1 (day 1 of training intervention) - Training 17 (day 21 of training intervention) - Posttest (day 22 of training intervention) |
| Change in the blood concentration of creatine kinase | Change in blood concentration of creatine kinase (marker of muscle damage) | Pretest - Training 2 (day 3 of training intervention) - Posttest (day 22 of training intervention) |
| Change in the blood concentration of Interleukin 6 (IL-6) | Change in blood concentration of Interleukin 6 (IL-6; marker of inflammation) | Pretest - Training 2 (day 3 of training intervention) - Posttest (day 22 of training intervention) |
| Change in the blood concentration of N-terminal propeptide of type I procollagen (P1NP) | Change in blood concentration of N-terminal propeptide of type I procollagen (P1NP; marker of collagen synthesis) | Pretest - Training 2 (day 3 of training intervention) - Posttest (day 22 of training intervention) |
| D000602 |
| Amino Acids, Peptides, and Proteins |
| D000067796 | Whey |
| D008892 | Milk |
| D003611 | Dairy Products |
| D005502 | Food |
| D000066888 | Diet, Food, and Nutrition |
| D010829 | Physiological Phenomena |
| D019602 | Food and Beverages |