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This study aims to evaluate the effects of leucine and branched-chain amino acids supplementation on skeletal muscle remodeling signaling pathways induced by resistance exercise.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Leucine | Experimental |
| |
| BCAA | Experimental |
| |
| Placebo | Placebo Comparator |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Leucine supplementation | Dietary Supplement | 1 bout of resistance exercise and supplementation of 4.0 g of leucine + 5.6 g of alanine |
|
| Measure | Description | Time Frame |
|---|---|---|
| Protein synthesis | Phosphorylation of proteins involved in protein synthesis | 1 hour |
| Protein degradation | Expression of protein involved in proteolytic pathway | 1 hour |
| Inflammation | Expression of systemic and muscular cytokines | 1 hour |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Claudia R da Luz, Master Student | University of Sao Paulo | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University of São Paulo - School of Physical Education and Sports | São Paulo | São Paulo | 05508-030 | Brazil |
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| BCAA supplementation | Dietary Supplement | 1 bout of resistance exercise and supplementation of 4.0 g of leucine + 2.8 g of isoleucine + 2.8 g of valine |
|
| Alanine supplementation | Dietary Supplement | 1 bout of resistance exercise and supplementation of 9.6 g of alanine |
|