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| Name | Class |
|---|---|
| Seoul National University Bundang Hospital | OTHER |
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Fluids administered intravenously may alter whole blood coagulation. However, little is known about the dose-response relationships of hemodilution in plasmalyte-148 solution. Investigators have therefore performed the present study to measure the effect of a plasmalyte-148 solution on the coagulation pathway according to the hemodilution level using a rotational thromboelastometry (ROTEM®) tests.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| 0% dilution | Blood specimen which was diluted with 0% level using a plasmalyte-148 solution | ||
| 20% dilution | Blood specimen which was diluted with 20% level using a plasmalyte-148 solution |
| |
| 40% dilution | Blood specimen which was diluted with 40% level using a plasmalyte-148 solution |
| |
| 60% dilution | Blood specimen which was diluted with 60% level using a plasmalyte-148 solution |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Plasmalyte-148 | Other | Venous blood is taken from 12 healthy volunteers and divided into four specimen bottles, which were diluted with different levels (0%, 20%, 40%, and 60%) using a plasmalyte-148 solution. |
| Measure | Description | Time Frame |
|---|---|---|
| FIBTEM | Fibrinolytic pathway values of rotational thromboelastometry analysis/ FIBTEM is not an acronym. | During the rotational thromboelastometry analysis/ an average of 1 hour |
| Measure | Description | Time Frame |
|---|---|---|
| INTEM | Intrinsic pathway values of rotational thromboelastometry analysis/ INTEM is not an acronym. | During the rotational thromboelastometry analysis/ an average of 1 hour |
| EMTEM | Extrinsic pathway values of rotational thromboelastometry analysis/ EXTEM is not an acronym. |
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Inclusion Criteria:
Exclusion Criteria:
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Healthy volunteers
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| Name | Affiliation | Role |
|---|---|---|
| Hyun-Jung Shin, PhD | Seoul National University Bundang Hospital | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Seoul National University Bundang Hospital | Seongnam-si | 13620 | South Korea |
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| ID | Term |
|---|---|
| D001778 | Blood Coagulation Disorders |
| ID | Term |
|---|---|
| D006402 | Hematologic Diseases |
| D006425 | Hemic and Lymphatic Diseases |
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| During the rotational thromboelastometry analysis/ an average of 1 hour |