Efficacy and Safety of Angelica Gigas N. Extract on Improvement of Blood Triglyceride

A 12-week, Randomized, Double-blind, Placebo-controlled Human Trial to Evaluate the Efficacy and Safety of Angelica Gigas N. Extract on Improvement of Blood Triglyceride

This study was conducted to investigate the effects of daily supplementation of Angelica gigas N. extract on improvement of Blood Triglyceride.

This study was a 12 weeks, randomized, double-blind, placebo-controlled human trial. Twenty subjects were randomly divided into Angelica gigas N. extract or a placebo group. Fasting triglyceride profiles before and after the intervention.

Inclusion Criteria:

• Age 19-80 years with Triglyceride 130-200 mg/dL

Exclusion Criteria:

• Lipid lowering agent within past 6 months

• Severe cardiovascular disease(Mvocardial infarction, Stroke, etc)

• Renal disease(Heredity hyperlipidemia, Acute/Chronic renal failure, Nephrotic syndrome, etc)

• Cancer, Respiratory organ disease(Asthma, Chronic obstructive pulmonary disease)

• Autoimmune disease

• Diabetes mellitus

• Allergic or hypersensitive to any of the ingredients in the test products

• History of disease that could interfere with the test products or impede their absorption

• Under antipsychotic drugs therapy within past 2 months

• History of alcohol or substance abuse

• Participation in any other clinical trials within past 2 months

• Laboratory test by show the following results

  • aspartate aminotransferase, alanine aminotransferase > Reference range upper limit treble
  • Serum Creatinine > 2.0 mg/dl

• Pregnancy or breast feeding

• Not Contraception(except: Surgery for female infertility)