Efficacy and Safety of Hydrolyzed Ginseng Extract on Impaired Fasting Glucose

An 8 Weeks, Randomized, Double-blind, Placebo-controlled Clinical Trial for Anti-diabetic Effects of Hydrolyzed Ginseng Extract

This study was conducted to investigate the effects of daily supplementation of hydrolyzed ginseng extract(HGE) on glycemic status in subjects with impaired fasting glucose(IFG).

This study was a 8 weeks, randomized, double-blind, placebo-controlled trial. Twenty subjects were randomly divided into HGE or a placebo group. Fasting and postprandial glucose profiles during oral glucose tolerance test (OGTT) were assessed before and after the intervention.

Inclusion Criteria:

• Age 20-70 years with fasting glucose 100~126 mg/dL

Exclusion Criteria:

• Abnormal lipid profile values
• Acute/chronic inflammation
• Treated with corticosteroid within past 4 weeks
• Cardiovascular disease
• Allergic or hypersensitive to any of the ingredients in the test products
• History of disease that could interfere with the test products or impede their absorption
• Participation in any other clinical trials within past 2 months
• Renal disease
• Abnormal hepatic function
• Under hypolipidemic drugs therapy within past 3 months
• Under antipsychotic drugs therapy within past 2 months
• Laboratory test, medical or psychological conditions deemed by the investigators to interfere with successful participation in the study
• History of alcohol or substance abuse
• Pregnancy or breast feeding