A 8-week, Randomized, Double-blind, Placebo-controlled 2x2 Cross-over Design Human Trial to Evaluate the Efficacy and Safety of Angelica Gigas N. Extract on Improvement of Hyperglycemia
A 8-week, Randomized, Double-blind, Placebo-controlled 2x2 Cross-over Design Human Trial to Evaluate the Efficacy and Safety of Angelica Gigas N. Extract on Improvement of Hyperglycemia
This study was conducted to investigate the effects of daily supplementation of Angelica gigas N. extract on improvement of Hyperglycemia .
This study was a 8 weeks, randomized, double-blind, placebo-controlled 2×2 cross-over design human trial. Twenty subjects were randomly divided into Angelica gigas N. extract or a placebo group. Fasting and postprandial glucose profiles during oral glucose tolerance test (OGTT) were assessed before and after the intervention.
Inclusion Criteria:
Exclusion Criteria:
Weight less than 48 kg or weight decreased by more than 10% within past 3 months
Hypoglycemic agent, Obesity medicine, Lipid lowering agent within past 6 months or Blood sugar, Obesity and Lipid improvement functional foods within past 2 weeks
Treated with corticosteroid within past 4 weeks
Severe cardiovascular disease(Mvocardial infarction, Stroke, etc)
Renal disease(Heredity hyperlipidemia, Acute/Chronic renal failure, Nephrotic syndrome, etc)
Rheumatoid arthritis, Autoimmune disease
Cancer, Respiratory organ disease(Asthma, Chronic obstructive pulmonary disease)
Allergic or hypersensitive to any of the ingredients in the test products
History of disease that could interfere with the test products or impede their absorption
Under antipsychotic drugs therapy within past 2 months
History of alcohol or substance abuse
Participation in any other clinical trials within past 2 months
Laboratory test by show the following results
Pregnancy or breast feeding
Not Contraception(except: Surgery for female infertility)