Effects of Berry Peel Intake on Glucose Metabolism in Healthy Subjects

Effects of Berry Peel Intake on Glucose Metabolism in Healthy Subjects

The main objective of this study is to investigate the effect of a 4-weeks intake of berry peel powder on fasting and postprandial glucose metabolism and inflammatory markers. The berry peel product will be compared with a placebo in a single-blind, cross-over design. Furthermore, inflammation-related peripheral blood mononuclear cells (PBMCs) genes expression, appetite and cognitive performance will be included as a pilot study. Investigators hypothesize that long-term consumption of polyphenols and fibres of berry peel will exhibit both direct and indirect actions in healthy overweight subjects by improvement of glucose-associated markers as well as ameliorating inflammation. Moreover, above metabolic markers will correlated with improvements in inflammation-related PBMCs genes expression, subjective appetite and cognitive performance after long-term consumption of berry peel as a source of polyphenols.

Inclusion Criteria:

• Healthy males and females
• Signed informed consent
• BMI 25-30 kg/m2
• Must be able to accept plant-based foods/drinks

Exclusion Criteria:

• Below 18 years or above 40 years
• Smoking or using snuff
• vegetarian or vegan
• Stressed by venous blood sampling or previous experience of being difficult canulation