Rapid Versus Slow Ingestion of Mixed Meal: Influence on Islet and Incretin Hormone Secretion in Healthy Volunteers

Rapid Versus Slow Ingestion of Mixed Meal: Influence on Islet and Incretin

To test the influence of rapid versus slow ingestion of a mixed meal on insulin and incretin hormone secretion in healthy volunteers

A mixed meal (524 kcal) is ingested rapidly (within 5 min) or slowly (10-15 min) and changes in insulin, glucagon, GIP and GLP-1 levels are followed for subsequent 300 min

Inclusion Criteria:

• Healthy subjects

Exclusion Criteria:

• Diabetes Liver disease Kidney disease Thyroid disease