Gut Hormones After Meal Ingestion in Males Versus Females

Effects of Varying Meal Size on Gut Hormone and Islet Hormone Secretion in Males Versus Females

The study hypothesis is that the release of gut hormones is increased proportionally to caloric load in each meal. Three different meals with different meal size will therefore be served and gut hormones determined.

In healthy males and females, meals with 511, 743 and 1034 kcal will be given orally. Samples will be taken during the following 300 min and gut hormones (glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1) will be determined along with insulin and glucagon levels.

Inclusion Criteria:

• Healthy status

Exclusion Criteria:

• Diabetes
• Liver disease
• kidney disease
• thyroid disease