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| ID | Type | Description | Link |
|---|---|---|---|
| 1R21DA029708 | U.S. NIH Grant/Contract | View source |
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| Name | Class |
|---|---|
| National Institute on Drug Abuse (NIDA) | NIH |
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This research is being done to learn if computer tasks that challenge the brain (cognitively stimulating tasks) can improve memory and other types of thinking. The study will compare the effects of different versions of the computer tasks. It also will compare the task performance of different groups of people.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Adaptive cognitively stimulating activities | Experimental |
| |
| Non-adaptive cognitively stimulating activities | Active Comparator |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Computerized cognitively stimulating activities | Behavioral | The study will compare the effects of different methods of computerized mental stimulation. The intervention involves 25 sessions involving computerized cognitive tasks. |
| Measure | Description | Time Frame |
|---|---|---|
| Working Memory | Change in maximum number of digits correctly recalled in Digit Span Backwards task, from baseline to 7 weeks | baseline, 7 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| Episodic Memory | baseline, 7 weeks | |
| Trail-making | baseline, 7 weeks | |
| go/No-go |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Miriam Z Mintzer, PhD | Johns Hopkins University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| BPRU, Johns Hopkins Bayview Medical Center | Baltimore | Maryland | 21224 | United States |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 26404954 | Derived | Rass O, Schacht RL, Buckheit K, Johnson MW, Strain EC, Mintzer MZ. A randomized controlled trial of the effects of working memory training in methadone maintenance patients. Drug Alcohol Depend. 2015 Nov 1;156:38-46. doi: 10.1016/j.drugalcdep.2015.08.012. Epub 2015 Aug 24. |
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| ID | Title | Description |
|---|---|---|
| FG000 | Adaptive Cognitively Stimulating Activities | Computerized cognitively stimulating activities: The study will compare the effects of different methods of computerized mental stimulation. The intervention involves 25 sessions involving computerized cognitive tasks. |
| FG001 | Non-adaptive Cognitively Stimulating Activities | Computerized cognitively stimulating activities: The study will compare the effects of different methods of computerized mental stimulation. The intervention involves 25 sessions involving computerized cognitive tasks. |
| Title | Milestones | Reasons Not Completed | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Overall Study |
|
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| ID | Title | Description |
|---|---|---|
| BG000 | Cognitively Stimulating Activities | Computerized cognitively stimulating activities: The study will compare the effects of different methods of computerized mental stimulation. The intervention involves 25 sessions involving computerized cognitive tasks. |
| BG001 | Cognitively Stimulating Activities: Other |
| Units | Counts |
|---|---|
| Participants |
|
| Title | Description | Population Description | Parameter Type | Dispersion Type | Unit of Measure | Calculate Percentage | Denominator Units Selected | Denominators | Classes |
|---|---|---|---|---|---|---|---|---|---|
| Age, Continuous | Mean |
| Type | Title | Description | Population Description | Reporting Status | Anticipated Posting Date | Parameter Type | Dispersion Type | Unit of Measure | Calculate Percentage | Time Frame | Units Analyzed | Denominator Units Selected | Arm/Group Information | Denominators | Classes | Analyses | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Primary | Working Memory | Change in maximum number of digits correctly recalled in Digit Span Backwards task, from baseline to 7 weeks | Posted | Mean | Standard Deviation | digits recalled | baseline, 7 weeks |
|
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| ID | Title | Description | Deaths (Affected) | Deaths (At Risk) | Serious Events (Affected) | Serious Events (At Risk) | Other Events (Affected) | Other Events (At Risk) |
|---|---|---|---|---|---|---|---|---|
| EG000 | Cognitively Stimulating Activities | Computerized cognitively stimulating activities: The study will compare the effects of different methods of computerized mental stimulation. The intervention involves 25 sessions involving computerized cognitive tasks. |
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| Title | Organization | Phone | Extension | |
|---|---|---|---|---|
| Dr. Miriam Mintzer | Johns Hopkins University School of Medicine | 410 550-0529 | mmintzer@jhmi.edu |
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| ID | Term |
|---|---|
| D019966 | Substance-Related Disorders |
| ID | Term |
|---|---|
| D064419 | Chemically-Induced Disorders |
| D001523 | Mental Disorders |
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| baseline, 7 weeks |
| Addiction Severity Index | baseline, 7 weeks |
| Delay Discounting | baseline, 7 weeks |
| Digit Symbol Substitution Test | baseline, 7 weeks |
Computerized cognitively stimulating activities: The study will compare the effects of different methods of computerized mental stimulation. The intervention involves 25 sessions involving computerized cognitive tasks. |
| BG002 | Total | Total of all reporting groups |
| years |
|
| Sex: Female, Male | Count of Participants | Participants |
|
| Region of Enrollment | Number | participants |
|
|
|
| Secondary | Episodic Memory | Not Posted | baseline, 7 weeks |
| Secondary | Trail-making | Not Posted | baseline, 7 weeks |
| Secondary | go/No-go | Not Posted | baseline, 7 weeks |
| Secondary | Addiction Severity Index | Not Posted | baseline, 7 weeks |
| Secondary | Delay Discounting | Not Posted | baseline, 7 weeks |
| Secondary | Digit Symbol Substitution Test | Not Posted | baseline, 7 weeks |
| 0 |
| 37 |
| 0 |
| 37 |
| EG001 | Cognitively Stimulating Activities: Other | Computerized cognitively stimulating activities: The study will compare the effects of different methods of computerized mental stimulation. The intervention involves 25 sessions involving computerized cognitive tasks. | 0 | 36 | 0 | 36 |
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