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| ID | Type | Description | Link |
|---|---|---|---|
| R01AG034934 | U.S. NIH Grant/Contract | View source |
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| Name | Class |
|---|---|
| National Institute on Aging (NIA) | NIH |
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The purpose of this study is to learn if activities that challenge the brain (mentally stimulating activities) can improve memory and other types of thinking in patients with Mild Cognitive Impairment. The study will compare the effects of different methods of mental stimulation.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Mentally stimulating activities | Experimental |
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| Mentally stimulating activities- other | Active Comparator |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| mentally stimulating activities | Behavioral | The study will compare the effects of different methods of mental stimulation. The intervention involves 6 classroom-style educational sessions and 10 mental stimulation studies involving computerized memory tasks. |
| Measure | Description | Time Frame |
|---|---|---|
| Self-Ordered Pointing Task | baseline | |
| Trail-Making | baseline | |
| Timed Instrumental Activities of Daily Living | baseline | |
| Rey Auditory Verbal Learning Test | baseline | |
| Self-ordered pointing task | immediately after the intervention | |
| Self-ordered pointing task | 3 months post intervention | |
| Self-ordered pointing task | 9 months post-intervention | |
| Trail-Making | immediately after the intervention | |
| Trail-Making | 3 months post-intervention | |
| Trail-Making | 9 months post-intervention | |
| Timed Instrumental Activities of Daily Living | immediately after the intervention | |
| Timed Instrumental Activities of Daily Living |
| Measure | Description | Time Frame |
|---|---|---|
| Clinical Dementia Rating Scale | baseline, immediately after the intervention, 3 months post intervention, and 9 months post-intervention | |
| Digit Symbol Substitution Test | baseline, immediately after the intervention, 3 months post intervention, and 9 months post-intervention |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Paul B Rosenberg, MD | Johns Hopkins University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| BPRU, Johns Hopkins Bayview Medical Center | Baltimore | Maryland | 21224 | United States |
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| ID | Term |
|---|---|
| D060825 | Cognitive Dysfunction |
| ID | Term |
|---|---|
| D003072 | Cognition Disorders |
| D019965 | Neurocognitive Disorders |
| D001523 | Mental Disorders |
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| 3 months post-intervention |
| Timed Instrumental Activities of Daily Living | 9 months post-intervention |
| Rey Auditory Verbal Learning Test | immediately after the intevention |
| Rey Auditory Verbal Learning Test | 3 months post-intervention |
| Rey Auditory Verbal Learning Test | 9 months post-intervention |
| Digit Span | baseline, immediately after the intervention, 3 months post intervention, and 9 months post-intervention |
| Verbal Fluency Test | baseline, immediately after the intervention, 3 months post intervention, and 9 months post-intervention |
| Geriatric Depression Scale | baseline, immediately after the intervention, 3 months post intervention, and 9 months post-intervention |
| Neuropsychiatric Inventory | baseline, immediately after the intervention, 3 months post intervention, and 9 months post-intervention |
| Recollection Task | baseline, immediately after the intervention, 3 months post intervention, and 9 months post-intervention |
| N-Back | baseline, immediately after the intervention, 3 months post intervention, and 9 months post-intervention |
| Rivermead Behavioral Memory Test | baseline, immediately after the intervention, 3 months post intervention, and 9 months post-intervention |
| Instrumental Activities of Daily Living | baseline, immediately after the intervention, 3 months post intervention, and 9 months post-intervention |
| Functional Capacities for Activities of Daily Living | baseline, immediately after the intervention, 3 months post intervention, and 9 months post-intervention |
| Multifactorial Memory Questionnaire | baseline, immediately after the intervention, 3 months post intervention, and 9 months post-intervention |