Effects of Mental Stimulation in Patients With Mild Cognitive Impairment

A Theoretically Based Memory Training Intervention in Mild Cognitive Impairment

The purpose of this study is to learn if activities that challenge the brain (mentally stimulating activities) can improve memory and other types of thinking in patients with Mild Cognitive Impairment. The study will compare the effects of different methods of mental stimulation.

Inclusion Criteria:

• ≥ 50 years of age
• meet criteria for amnestic-Mild Cognitive Impairment (MCI)
• have capacity to give informed consent
• have capacity to complete assessment measures

Exclusion Criteria:

• history of drug or alcohol dependence
• severe psychiatric conditions associated with psychosis (e.g., schizophrenia)
• recent stroke
• clinical diagnosis of probable Alzheimer's Disease
• history of seizure disorder, serious head trauma, or other medical, psychiatric, or neurological conditions associated with significant cognitive impairment (e.g., Parkinson's Disease, Korsakoff's, HIV)
• current use of Alzheimer's Disease medications (e.g., cholinesterase inhibitors, memantine)