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This study examines whether computer tasks can improve memory and other cognitive functions among patients receiving inpatient treatment for substance use disorders.
Participants will complete cognitive training sessions on a regular basis during inpatient treatment. Alternate versions of the computer tasks will be compared in a randomized design. Primary and secondary outcomes will consist of changes in cognitive performance before and after the training period.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Experimental | Experimental | Computerized cognitive training activities |
|
| Control | Active Comparator | Non-adaptive computerized cognitive training activities |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Cognitive training activities | Behavioral | Training activities consist of computer tasks designed to improve memory and cognition. The intervention consists of 45-minute training sessions delivered regularly during inpatient treatment. |
| Measure | Description | Time Frame |
|---|---|---|
| Auditory memory capacity - WAIS Digit Span score | WAIS Digit Span score | Baseline, 3 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| Auditory memory capacity - WAIS Letter-number sequencing score | WAIS Letter-number sequencing score | Baseline to 3 weeks |
| Visual memory capacity - WMS Spatial span score | WMS Spatial span score |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Christian Hendershot, PhD | Centre for Addiction and Mental Health | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Centre for Addiction and Mental Health | Toronto | Ontario | Canada |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 30475014 | Derived | Hendershot CS, Wardell JD, Vandervoort J, McPhee MD, Keough MT, Quilty LC. Randomized trial of working memory training as an adjunct to inpatient substance use disorder treatment. Psychol Addict Behav. 2018 Dec;32(8):861-872. doi: 10.1037/adb0000415. Epub 2018 Nov 26. |
| Label | URL |
|---|---|
| The Centre for Addiction and Mental Health (CAMH) is the leading mental health and addictions research facility in Canada, and one of the largest in the world. | View source |
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| ID | Term |
|---|---|
| D019966 | Substance-Related Disorders |
| ID | Term |
|---|---|
| D064419 | Chemically-Induced Disorders |
| D001523 | Mental Disorders |
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| Inpatient psychosocial therapy | Behavioral | Group psychosocial therapy delivered in an inpatient setting. |
|
| Baseline to 3 weeks |
| Visual memory capacity - WMS Symbol span score | WMS Symbol span score | Baseline to 3 weeks |
| Training progress score - Cognitive progress indicator score | Cognitive progress indicator score | Baseline to 4 weeks |