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NCT07715786

Overview

NCT ID: NCT07715786
Lead Sponsor: Toros UniversityOTHER
Official Title: Comparison of Hamstring Muscle Oxygenation Responses During Nordic Hamstring Exercise and Blood Flow Restriction Nordic Hamstring Exercise in Elite Adolescent Athletes: A Crossover Experimental Study
Brief Summary: This crossover experimental study aims to compare acute hamstring muscle oxygenation responses during Nordic Hamstring Exercise (NHE) and Blood Flow Restriction Nordic Hamstring Exercise (BFR-NHE) in elite adolescent athletes. Participants will complete both exercise conditions in a randomized order separated by a 7-day washout period. Muscle oxygen saturation will be assessed using near-infrared spectroscopy (MOXY), together with total hemoglobin responses, blood lactate concentration, perceived exertion, and exercise performance variables. The findings may improve understanding of the physiological effects of blood flow restriction during eccentric hamstring exercise in adolescent athletes.
Conditions: Healthy Volunteers (HV)

Status and Timeline

Status: Recruiting
Last Update Posted: Jul 20, 2026Actual
Start Date: Jul 1, 2026Actual
Primary Completion Date: Jul 2027Estimated
Completion Date

Participation Criteria

Ages Eligible for Study: Child (0-17)Adult (18-64)
Sexes Eligible for Study: All
Accepts Healthy Volunteers?: Yes
Eligibility Criteria: Inclusion Criteria:

Elite adolescent athletes aged 14 to 18 years.

Licensed athletes with at least 3 years of regular sports participation.

Currently participating in a regular weekly training program.

Physically able to complete the Nordic Hamstring Exercise and study testing protocol.

Willing to participate in the study.

Able to provide written informed consent.

For participants younger than 18 years, written informed consent provided by a parent or legal guardian and assent provided by the participant.

Exclusion Criteria:

Hamstring injury within the previous 6 months.

Lower extremity surgery within the previous 6 months.

Current lower extremity pain or musculoskeletal injury that may interfere with exercise performance.

Cardiovascular, vascular, neurological, or other medical conditions that may contraindicate blood flow restriction exercise.

Presence of skin lesions or conditions preventing placement of the blood flow restriction cuff or MOXY sensor.

Inability to complete either exercise condition or follow the study protocol.

Study Plan

Study Type: Interventional
Phase: Not Applicable
Enrollment: 24Estimated
Primary Purpose: Other
Allocation: Randomized
Interventional Model: Crossover Assignment
Masking: None (Open Label)

Contacts and Locations

Central Contacts: İdil Ünlü, Assist. Prof. Dr.Contact
idil.unlu@toros.edu.tr+90 506 515 66 22

Similar Studies

Participant Group/Arms

BFR NHE-NHEExperimental

Participants randomized to this sequence will perform conventional Nordic Hamstring Exercise during the first testing session. Following a 7-day washout period, they will perform Nordic Hamstring Exercise with blood flow restriction during the second testing session.

Other: Nordic Hamstring Exercise

Other: Blood Flow Restriction Nordic Hamstring Exercise

NHE-BFR NHEExperimental

Participants randomized to this sequence will perform Nordic Hamstring Exercise with blood flow restriction during the first testing session. Following a 7-day washout period, they will perform conventional Nordic Hamstring Exercise during the second testing session.

Other: Nordic Hamstring Exercise