Injectable Alloplastic Bone Graft for Socket Preservation: Clinical, Radiographic, and Histological Evaluation

Clinical, Radiographic, and Histological Evaluation of Injectable Alloplastic Bone Graft in Extraction Socket Preservation

This study will evaluate the clinical efficacy of injectable alloplastic bone grafts in terms of radiography and histology in order to preserve tooth sockets following extraction. Methodology: Twenty new extraction sockets from twenty surgically extracted non-restorable mandibular molar teeth will be used in this clinical investigation.

Using computer randomization (http://www.randomlists.com), the 20 extraction sockets will be split into two equal groups (n=10) at random. Ten sockets (the experimental group) will undergo socket preservation using injectable bone substitute biomaterial. To permit normal physiological healing, the remaining 10 sockets (control group) will left unfilled. Clinical examination will be carried out after 2 days, 1 week, 2 weeks, 1 month, and 4 months, while after 4 months, radiographic measurements of bone dimension changes were carried out, and the histological inspection will be carried out three months after the removal of the tooth.

Inclusion Criteria:

• Patient aged between 40 and 60 years.
• General good health.
• Presence of a hopeless mandibular posterior tooth that requires extraction.
• Volunteer subjects have to voluntarily sign an informed consent.
• Patient Indicated for implant.

Exclusion Criteria:

• Patient with systemic disease affection bone metabolism.
• Large periapical radiographic changes related to the tooth to be Extracted, in the form of abscess, granuloma, or cyst.
• Teeth need trans-alveolar extraction.
• Patients with contraindication to surgical treatment.
• Patients suffering from a psychological disorder.
• Patients with uncontrolled medical conditions.