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To assess the anti-aging efficacy of Marine Collagen Peptides on skin, hair and finger nails for human
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| placebo drink | Placebo Comparator |
| |
| Marine Collagen Peptides drinks | Experimental |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Marine Collagen Peptides | Dietary Supplement | consume 1 bottle per day |
|
| Measure | Description | Time Frame |
|---|---|---|
| The change of skin hydation | Corneometer® CM825 (CK, Germany) was utilized to measure skin surface hydation. Units: arbitrary Corneometer® units 0-120. | Change from Baseline skin skin hydation at 12 weeks |
| The change of skin wrinkles | VISIA Complexion Analysis was utilized to measure skin wrinkles. Units: the amount of detectable wrinkles | Change from Baseline skin wrinkles at 12 weeks |
| The change of skin elasticity | Cutometer® MPA580 was utilized to measure skin elasticity. Units: visco-elasticity in %. | Change from Baseline skin elasticity at 12 weeks |
| The change of skin collagen density | DermaLab® Series SkinLab Combo was utilized to measure skin collagen density. Units: arbitrary units | Change from Baseline skin collagen density at 12 weeks |
| The change of hair diameters | Mitutoyo C/N293-100 was utilized to measure hair diameters. Units: millimeter | Change from Baseline hair diameters at 12 weeks |
| The change of hair loss amount | Collect and measure the weight of loss hair. Units: gram | Change from Baseline hair loss amount at 12 weeks |
| The change of hair roots diameters | Mitutoyo C/N293-100 was utilized to measure hair roots diameters. Units: millimeter |
| Measure | Description | Time Frame |
|---|---|---|
| The change of self-assessment skin, hair, and nails condition | A self-assessment questionnaire was collected and evaluate skin, hair, and nails condition | Change from Baseline skin, hair, and nails condition at 12 weeks |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Chia-Hua Liang, Ph.D. | Chia Nan University of Pharmacy ＆ Science | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Chia Nan University of Pharmacy & Science | Pingtung City | 928 | Taiwan |
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| ID | Term |
|---|---|
| D012871 | Skin Diseases |
| D009263 | Nails, Ingrown |
| ID | Term |
|---|---|
| D017437 | Skin and Connective Tissue Diseases |
| D009260 | Nail Diseases |
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| placebo drink | Dietary Supplement | consume 1 bottle per day |
|
| Change from Baseline hair roots diameters at 12 weeks |
| The change of hair density | Soft Plus was utilized to picture and observe hair density. | Change from Baseline hair density at 12 weeks |
| The change of hair follicle strength | Pull up the hair of the frontal bone, temporal bone and occipital bone (approximately 60 hairs/area) to assess the number of hair loss in each area. Units: the number of loss hair | Change from Baseline hair follicle strength at 12 weeks |
| The change of thumbs nail color | Chroma Meter MM500 was utilized to measure thumbs nail color. Units: L* index | Change from Baseline thumbs nail color at 12 weeks |
| The change of nails appearence | Picture taken was utilized to record and observe nails appearence. | Change from Baseline nails appearence at 12 weeks |
| The change of nails growth | Marking the position of middle fingers lunula was utilized to record and observe nails growth. Units: milimeter | Change from Baseline marking position at 12 weeks |
| The degree of nails fragility | Iron ruler was utilized to evaluate nails fragility. Picture taken was utilized to record and observe the change of nails fragility. | Change from Baseline nails fragility at 12 weeks |