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| Name | Class |
|---|---|
| Princeton Consumer Research | OTHER |
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The BECOME Study (Bovine and Marine Collagen Efficacy for Skin, Hair, Nails and Whole Body Health Markers Evaluation) is a randomized controlled trial designed to compare the effects of bovine and marine collagen supplements versus a placebo on skin, hair, nails and whole body health markers. The trial aims to determine the most efficacious collagen source for improving health outcomes and to establish if both types of collagen are equally effective. Participants will be assessed on various health parameters, including skin elasticity, joint health, digestive health, and overall well-being, over a specified period.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Bovine Collagen | Active Comparator | 10g powder format taken daily for duration of the study. |
|
| Marine Collagen | Active Comparator | 10g powder format taken daily for duration of the study. |
|
| Placebo | Placebo Comparator |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Bovine or Marine Collagen | Dietary Supplement | Bovine or Marine Collagen |
|
| Measure | Description | Time Frame |
|---|---|---|
| Change in nail strength and growth | Assessment of nail strength and growth will be assessed by self-perception questionnaire | Baseline, week 6 and week 12 |
| Change in skin elasticity | Changes in skin elasticity will be measured by a cutometer | Baseline, week 6 and week 12 |
| Change in hair thickness and strength | Strength and breakage of hair will be assessed by self perception questionnaire | Baseline, week 6 and week 12 |
| Change in skin wrinkles | Measurement of the reduction in skin wrinkles using Profilometer | Baseline, week 6 and week 12 |
| Change in perceived skin health | Changes in perceived skin health assessed by self perception questionnaire | Baseline, week 6 and week 12 |
| Change in skin wrinkles by visual assessment | Change in skin wrinkles will be performed by visual assessment by a dermatologist | Baseline, week 6 and week 12 |
| Changes in skin pigmentation | Changes in skin pigmentation will be assessed by Chromameter | Baseline, week 6 and week 12 |
| Changes in skin hydration |
| Measure | Description | Time Frame |
|---|---|---|
| Digestive Quality of Life (DQDL) Assessment | Participants will complete a Digestive Quality of Life (DQDL) Assessment to evaluate the digestive health benefits | Baseline, week 6 and week 12 |
| Subjective Perception Questionnaire |
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Inclusion Criteria:
Females aged 35-55 years. Participants must be comfortable with bovine or marine collagen (non-vegan/vegetarian).
Must provide informed consent and be willing to comply with study requirements.
Exclusion Criteria:
Pregnant or breastfeeding women. History of chronic skin conditions (e.g., eczema, psoriasis) that might interfere with study outcomes.
Any active skin infections or severe acne. Currently taking collagen supplements or have taken them within the last 6 months.
Use of medications or topical agents that can affect skin, hair, nails, or gastrointestinal health (e.g., corticosteroids, retinoids).
Excessive alcohol consumption or current smokers. Regular use of sunbeds. Recent cosmetic procedures (e.g., Botox, fillers, chemical peels, laser treatments) on skin, hair, or nails within the last 3 months.
Any condition or situation that, in the opinion of the investigator, may interfere with the participant's ability to comply with the study requirements or give informed consent.
Poor adherence to previous study protocols
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Jenna Macciochi, PhD | Contact | +447799090189 | jenna@ancientandbrave.earth | |
| Becky Clarke | Contact | beckyclarke@princetonconsumer.com |
| Name | Affiliation | Role |
|---|---|---|
| Jenna Macciochi, PhD | jenna@ancientandbrave.earth | Principal Investigator |
| Becky Clarke | Princeton Consumer Research | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Princeton Consumer Research, 8 Richmond Road, Dukes Park | Recruiting | Chelmsford | Essex | CM2 6UA | United Kingdom |
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| ID | Term |
|---|---|
| D003483 | Cutis Laxa |
| D000505 | Alopecia |
| ID | Term |
|---|---|
| D012873 | Skin Diseases, Genetic |
| D030342 | Genetic Diseases, Inborn |
| D009358 | Congenital, Hereditary, and Neonatal Diseases and Abnormalities |
| D003240 | Connective Tissue Diseases |
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Changes in skin hydration will be assessed by a Corneometer
| Baseline, week 6 and week 12 |
Subjective Perception Questionnaire (SPQ) for Whole Body Health to capture participants' self-reported perceptions of their overall health and well-being
| Baseline, week 6 and week 12 |
| D017437 | Skin and Connective Tissue Diseases |
| D012871 | Skin Diseases |
| D007039 | Hypotrichosis |
| D006201 | Hair Diseases |
| D020763 | Pathological Conditions, Anatomical |
| D013568 | Pathological Conditions, Signs and Symptoms |