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The purpose of this study is to assess the efficacy and safety of microneedle patch with botulinum toxin for improving enlarged pores.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Microneedle patch with Botulinum toxin | Experimental | Participants recieve microneedle path with 20 units Botulinum toxin at nose and cheek one side. |
|
| Intradermal Botulinum toxin injection | Active Comparator | Participants recieve intradermal 20 units Botulinum toxin injection at nose and cheek in other side. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Microneedle patch | Device | with 20 units botulinum toxin |
| |
| Measure | Description | Time Frame |
|---|---|---|
| Change from baseline of enlarged pores as measured by VISIA (pores parameter) and using pore score | the used pore scores, patients with visible pores took the score "1," and those with enlarged pores took "2." When black heads were embedded on facial pores the score was "3." The scores were assessed by 2 investigators who were blinded to the treatment used on each side. | Post-intervention, week 4 and week 16 |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Chotip Jitudomtham, MD | Dhurakij Pundit University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Dhurakij Pundit University | Lak Si | Bangkok | Thailand |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 36606384 | Result | Salem RM, Salah SAE, Ibrahim SE. Microbotox injection versus its topical application following microneedling in the treatment of wide facial pores: A split face comparative study. J Cosmet Dermatol. 2023 Apr;22(4):1249-1255. doi: 10.1111/jocd.15590. Epub 2023 Jan 6. |
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| ID | Term |
|---|---|
| D007271 | Injections, Intradermal |
| ID | Term |
|---|---|
| D007279 | Injections, Subcutaneous |
| D007267 | Injections |
| D004333 | Drug Administration Routes |
| D004358 | Drug Therapy |
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| Intradermal injection |
| Device |
with 20 units botulinum toxin |
|
| D013812 |
| Therapeutics |