A Study of NT 201 in the Treatment of Enlarged Pores and Excessive Sebum Production in the Face

A Prospective, Randomized, Double-blind, Placebo-controlled, Multi-center Exploratory Study to Investigate NT 201 in the Treatment of Enlarged Pores and Excessive Sebum Production in the Face

The purpose of this study is to investigate the efficacy and safety of NT 201 injections in the treatment of enlarged pores and excessive sebum production in the face.

Eligible subjects will be randomized to one of the two treatment groups: NT 201 group and placebo in order to receive one session of injections with either NT 201 or placebo in the upper face (forehead and cheek area) on Day 1 and followed for about 90 days after treatment.

Inclusion Criteria:

• Cheek pore size assessed as "large" by the investigator
• Oily skin on the forehead

Exclusion Criteria:

• Treatment with Botulinum toxin (BoNT) of any serotype in the face within the last 12 months
• Facial cosmetic procedure (e.g., chemical peel, photo rejuvenation, mesotherapy, photodynamic therapy, laser treatment, ultrasound treatment, tattooing of eyebrows) within the last 12 months
• Treatment with any dermal filler in the face within the last 12 months
• Any previous insertion of permanent material in the face, including permanent dermal fillers (e.g., silicone, polymethyl methacrylate)
• Any medical condition that may put the subject at increased risk with exposure to botulinum toxin of any serotype