The aim of the present study is to determine if a regular oral supplementation of xanthohumol attenuate the severity of symptoms and duration of´viral infections.

In this placebo-controlled study, blood is taken on the first day of the study, followed by a 90-day intervention with xanthohumol or a placebo, which is taken twice daily. Blood samples will be taken on day 0, day 45 and day 90. Should the study participants develop a respiratory infection during the study, they will be asked to perform a self-test.

Inclusion Criteria:

• healthy
• BMI >18 kg/m² or < 28kg/m²

Exclusion Criteria:

• food intolerances
• food allergies
• chronic inflammatory diseases
• metabolic diseases
• viral or bacterial infections within the last 3 weeks of inclusion
• intake of immunosuppressive medication
• severe acute respiratory syndrome coronavirus type 2-infection in the last 4 months
• influenza infection in the "current" flu season