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| ID | Type | Description | Link |
|---|---|---|---|
| 7R01AG055425-07 | U.S. NIH Grant/Contract | View source |
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| Name | Class |
|---|---|
| Western University, Canada | OTHER |
| National Institute on Aging (NIA) | NIH |
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The aim of this study is to evaluate the effectiveness and feasibility of evidence-based interventions in individuals living with mild to moderate primary progressive aphasia (PPA) that address communication-focused outcomes.
The purpose of this study is to evaluate the effectiveness and feasibility of evidence-based interventions in individuals living with mild to moderate primary progressive aphasia (PPA) that address communication-focused outcomes. The study team aims to enhance the personal relevance and therapeutic impact of goal attainment scaling (GAS) while building self-efficacy within a self-management framework.
This study will be a continuation of one of the largest non-pharmacologic intervention studies for individuals with PPA to date. It will add critical information regarding the effectiveness of telepractice interventions for communication disorders in adults with primary progressive aphasia specifically, and in dementia more broadly. The goal of this study is to maximize functional communication and life participation for the participants.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Communication Bridgeâ„¢ | Experimental | Participants receive Communication Bridgeâ„¢, a multi-component, participation-focused, dyadic intervention in which both the person with PPA and their co-enrolled communication partner are intervention recipients. Communication Bridgeâ„¢ is modelled on the Living with Aphasia: Framework for Outcome Measurement (A-FROM) and the Care Pathway Model that was developed for persons living with primary progressive aphasia. Consistent with participation-focused intervention models personally salient training stimuli are incorporated into all therapy activities in the Experimental arm. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Communication Bridge | Behavioral | Evidence-based speech language therapy treatment will be compared and contrasted in the two arms of the study. |
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| Measure | Description | Time Frame |
|---|---|---|
| Change in Communication Participation Person Centered Goals | Goal Attainment Scaling, a 7-point rating scale with -3 representing 'no longer participating' and +3 representing 'exceeded goal'. Higher scores indicate better progress in goal achievement. | Time Frame: 2 assessment time points through study completion, an average of 5 months, including change over time |
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Inclusion Criteria (person with PPA):
Inclusion Criteria (Co-enrolled communication partner):
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Emily Roglaski, PhD | Professor of Neurology | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University of Chicago - American School Building | Chicago | Illinois | 60637 | United States |
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| ID | Term |
|---|---|
| D018888 | Aphasia, Primary Progressive |
| D001037 | Aphasia |
| D003704 | Dementia |
| D003142 | Communication |
| D057180 | Frontotemporal Dementia |
| D000544 | Alzheimer Disease |
| ID | Term |
|---|---|
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
| D009422 | Nervous System Diseases |
| D013064 | Speech Disorders |
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| D007806 | Language Disorders |
| D003147 | Communication Disorders |
| D019954 | Neurobehavioral Manifestations |
| D009461 | Neurologic Manifestations |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D019965 | Neurocognitive Disorders |
| D001523 | Mental Disorders |
| D001519 | Behavior |
| D057174 | Frontotemporal Lobar Degeneration |
| D057177 | TDP-43 Proteinopathies |
| D019636 | Neurodegenerative Diseases |
| D057165 | Proteostasis Deficiencies |
| D008659 | Metabolic Diseases |
| D009750 | Nutritional and Metabolic Diseases |
| D024801 | Tauopathies |