Effects of Sufentanil on the Intraoperative Hemodynamics

Effects of Sufentanil on the Intraoperative Hemodynamic Parameters in Patients Undergoing Extracranial-intracranial Bypass Surgery: a Prospective Randomized Controlled Trial

This study is a randomized, controlled trial. A total of 92 patients will be randomized to receive sufentanil or remifentanil during extracranial-intracranial bypass surgery.

Inclusion Criteria:

• Patients who undergo elective extracranial-intracranial bypass surgery
• American Society of Anesthesiologists grade 1,2,3
• Age > 18 years old

Exclusion Criteria:

• Refuse to participate to the study
• American Society of Anesthesiologists grade 4
• Body Mass Index < 18.5 kg/m2 or > 35 kg/m2
• Allergic history of opioid
• pregnant
• MAO Inhibitor user
• Severe respiratory insufficiency