Krill Oil and Resistance Exercise in Older Adults

The Effects of Krill Oil Supplementation on Adaptations in Muscle Strength, Function, Mass and Neuromuscular Function to a Pragmatic Home-based Resistance Exercise Intervention in Sedentary Older Adults: a Randomised Controlled Trial

The aim of this study is to determine whether krill oil supplementation enhances effects of a pragmatic resistance exercise programme on adaptations in muscle strength, mass, function and neuromuscular function in sedentary older adults. Hypothesis - krill oil supplementation will enhance the beneficial effects of resistance exercise on muscle strength, function, mass and neuromuscular function in sedentary older adults.

Inclusion Criteria:

• Over the age of 60 years
• scoring a low level of physical activity based on international physical activity questionnaire (not meeting the recommend physical activity which is at least 600 MET-min per week).

Exclusion Criteria:

• Diabetes
• severe cardiovascular disease
• seizure disorders
• uncontrolled hypertension (>150/90mmHg at baseline measurement)
• cancer or cancer that has been in remission <5 years
• ambulatory impairments which would limit ability to perform assessments of muscle function
• dementia
• taking medication known to affect muscle (e.g. steroids)
• have an implanted electronic device (e.g. pacemaker/defibrillator/insulin pump)
• on anticoagulant therapy
• allergies to seafood
• regular consumption of more than 1 portion of oily fish per week
• already taking fish or krill oil or other n3 PUFA supplements
• femoral neck fracture or other severe of hip or knee operations
• stroke
• Parkinson's disease
• COPD
• kidney disease
• hyperlipidaemia
• obesity
• osteoporosis.