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| ID | Type | Description | Link |
|---|---|---|---|
| 5R01DA002812-35 | U.S. NIH Grant/Contract | View source |
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| Name | Class |
|---|---|
| National Institutes of Health (NIH) | NIH |
| National Institute on Drug Abuse (NIDA) | NIH |
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In this study the investigator will assess the effect of a moderate dose of alcohol on emotional responses and feelings of connection during a dyadic semi-structured social interaction
The study will use a within-subject crossover design with four sessions, in which participants receive alcohol or placebo across sessions. During the four sessions, the participants will engage in a conversation with a stranger, and emotional responses and feelings of connection will be assessed.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Alcohol-alcohol | Experimental | Both conversation partners receive alcohol |
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| placebo-placebo | Placebo Comparator | Both conversation partners receive placebo |
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| alcohol-placebo | Experimental | participant receives alcohol and conversation partner receives placebo |
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| placebo-alcohol | Experimental | participant receives placebo and conversation partner receives alcohol |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Alcohol | Drug | Alcohol (0.8g/kg) |
| |
| Measure | Description | Time Frame |
|---|---|---|
| facial emotional responses | alterations in the rate of positive facial expressions during the conversation, measured by muscle action units. These will be compared between the drug and placebo sessions | during the length of the conversation (45 min) |
| self-reported feelings of connection | self-other overlap measure ratings 1-7, greater ratings indicates greater feelings of connection | at the end of each session (3.5 hrs post-drug administration). Changes across sessions will be assessed |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Harriet de Wit | University of Chicago | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University of Chicago | Chicago | Illinois | 60637 | United States |
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| ID | Term |
|---|---|
| D000428 | Alcohol Drinking |
| ID | Term |
|---|---|
| D004327 | Drinking Behavior |
| D001519 | Behavior |
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| ID | Term |
|---|---|
| D000431 | Ethanol |
| ID | Term |
|---|---|
| D000438 | Alcohols |
| D009930 | Organic Chemicals |
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| Placebo |
| Drug |
Placebo |
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