CompletedInterventionalEarly Phase 1Updated Jan 24, 2024
Behavior Brain Responses | NCT03964350 | Trialant
CompletedInterventionalEarly Phase 1Updated Jan 31, 2025
Behavior Brain Responses
Behavior and Brain Responses to Drugs
ClinicalTrials.gov ID
NCT03964350
Lead Sponsor
University of ChicagoOTHER
Overall Status
Completed
Study Type
Interventional
Phase
Early Phase 1
Enrollment
30Actual
Last Update Posted
Jan 31, 2025Actual
Start Date
May 28, 2019Actual
Primary Completion Date
Dec 31, 2020Actual
Completion Date
Dec 31, 2020Actual
Official Title
Behavior and Brain Responses to Drugs
Brief Summary
To compare responses to acute oral doses of ethanol in healthy young adults who experience mainly stimulant subjective effects from the drug or mainly sedative effects.
Alcohol Drinking
Drinking Behavior
Physiological Effects of Drugs
Central Nervous System Depression
Ethanol
Placebo
Ages Eligible for Study
Adult (18-64)
Sexes Eligible for Study
Male
Accepts Healthy Volunteers
Yes
Eligibility Criteria
21-35 years old
4-30 alcoholic drinks per week (as reported on PHQ or TLFB)
No 'flushing' reaction to alcohol
BMI 19-26
High school education or greater, fluent in English
No night shift work
No current or past year Axis I psychiatric disorder including drug/alcohol dependence
No current psychopharmacological treatment
No lifetime ADHD or prescription for ADHD medication
No abnormal EKG, cardiovascular illness, high blood pressure
No medical condition or pharmacological treatment for which alcohol is contraindicated
Not pregnant, lactating, or planning to become pregnant