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| Name | Class |
|---|---|
| Swedish Foundation for Strategic Research | OTHER |
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Aim of the study is to investigate health effects of oats and oat derived components, in human intervention studies, with the purpose to build new knowledge for development of cardiometabolic protective foods.
The overall goal is to increase the knowledge which can be used for the development of food products with anti-diabetic properties, with the purpose to facilitate healthier food choices for people. More specifically the primary purpose of this project is to evaluate effects in healthy humans on cardiometabolic test markers of oat and oat based product. The new knowledge will form a base for the development of oat based food products with added health values.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Oat meal 1 | Experimental | The test portion is based on 30 gram available carbohydrates with added x amount oat betaglucan. Test portion consumed as a breakfast meal prior to determinations of test variables in the morning |
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| Oat meal 2 | Experimental | The test portion is based on 30 gram available carbohydrates with added y amount of oat betaglucan. Test portion consumed as a breakfast meal prior to determinations of test variables in the morning |
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| Oat meal 3 | Experimental | The test portion is based on 30 gram available carbohydrates with added z amount of oat betaglucan. Test portion consumed as a breakfast meal prior to determinations of test variables in the morning |
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| Reference | Placebo Comparator | The test portion is based on 30 gram available carbohydrates without added oat betaglucan. Test portion consumed as a breakfast meal prior to determinations of test variables in the morning |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Effects of Oat and Oat Components on Cardiometabolic risk variables | Dietary Supplement | Oat and oat bioactive components consumed as breakfast meal. |
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| Measure | Description | Time Frame |
|---|---|---|
| Blood glucose regulation | Postprandial blood glucose regulation (incremental area under the curve) acute after intake of the test products and at forthcoming meals within 5.5 hours after consumption of test products. | Time Frame: 0 - 5.5 hours ( at fasting and then repeatedly after breakfast and Standardize lunch) |
| Measure | Description | Time Frame |
|---|---|---|
| Serum insulin | Acute effects of postprandial serum insulin concentrations (incremental area under the curve) after intake of the test products. | Time Frame: 0 - 5.5 hours ( at fasting and then repeatedly after breakfast and Standardize lunch) |
| Measure | Description | Time Frame |
|---|---|---|
| Subjective appetite sensations | Determined with VAS (visual analogue scale) scales (0-100 mm) as a range of subjective sensations related to appetite (such as hunger, desire to eat or fullness) | Time Frame: 0 - 5.5 hours ( at fasting and then repeatedly after breakfast and Standardize lunch) |
Inclusion Criteria:
- Healthy adults BMI 18.5 - 28 Kg/m2 Non smokers Consuming a non-vegetarian diet that follows the Nordic diet recommendation.
Exclusion Criteria:
- Fasting blood glucose concentration >6.1 mmol/l Known cardio-metabolic disease (e.g. diabetes, hypertension, metabolic syndrome).
Gastro-intestinal disorders such as IBS (irritable bowel syndrome) that can interfere with the study results, food allergies.
No antibiotics or probiotics should have been consumed within 4 weeks prior to and during the study.
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| Name | Affiliation | Role |
|---|---|---|
| Anne Nilsson | Department of Food Technology, Engineering and Nutrition, Lund Univesity | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Food Technology, engineering and Nutrition, LTH, Lund University | Lund | Skåne County | 22100 | Sweden |
Raw data
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