Omics Sequencing of Specimen Derived From Mother-Infant-Pairs

Omics Sequencing of Specimen Derived From Mother-Infant-Pairs

The investigators aim to collect breast-milk and feces from the participants, and apply culture techniques as well as omics sequencing technology to probe into the microbial and metabolomic signature of the specimens.

Inclusion Criteria:

• healthy pregnant women aged between 20y and 40y.
• Vaginal birth
• BMI<23.5 before pregnancy
• Infants' birth weight, between 2500g and 4000g.

Exclusion Criteria:

• gestational diabetes
• diagnosis of depressive disorder during pregnancy
• gestational hypertension
• diagnosis of other diseases during pregnancy
• Under probiotics or antibiotic treatment from 3 months prior to pregnancy till 3 months after delivery
• histrory of smoking and drinking alcohol
• history of diarrhea from 3 months prior to pregnancy till 3 months after delivery