Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
To assess cherry collagen drink on skin condition improvement
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Placebo drink | Placebo Comparator |
| |
| Cherry collagen drink | Experimental |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Cherry collagen drink | Dietary Supplement | consume 1 sachet per day |
|
| Measure | Description | Time Frame |
|---|---|---|
| The change of skin wrinkles | VISIA Complexion Analysis System was utilized to measure skin wrinkles. Units: arbitrary units | Change from Baseline skin wrinkles at 8 weeks |
| The change of skin texture | VISIA Complexion Analysis System was utilized to measure skin texture. Units: arbitrary units | Change from Baseline skin texture at 8 weeks |
| The change of skin collagen density | DermaLab® Series SkinLab Combo was utilized to measure skin pores. Units: arbitrary units | Change from Baseline skin collagen density at 8 weeks |
| The change of skin elasticity | Soft Plus was utilized to measure skin elasticity. Units: arbitrary units | Change from Baseline skin elasticity at 8 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| The change of skin melanin index | Soft Plus was utilized to measure skin melanin index. Units: arbitrary units | Change from Baseline skin melanin index at 8 weeks |
| The change of skin L* value | Chroma Meter MM500 was utilized to measure skin L* value. Units: arbitrary units, 0-100 |
| Measure | Description | Time Frame |
|---|---|---|
| The change of liver function biomarkers (AST, ALT) of blood | Venous blood was sampled to measure liver function biomarkers | Change from Baseline liver function biomarkers at 8 weeks |
| The change of renal function biomarkers (creatinine, BUN) of blood |
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Affiliation | Role |
|---|---|---|
| Chia-Hua Liang | Chia Nan University of Pharmacy ＆ Science | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Chia Nan University of Pharmacy & Science | Tainan | 71710 | Taiwan |
Not provided
| ID | Term |
|---|---|
| D012871 | Skin Diseases |
| ID | Term |
|---|---|
| D017437 | Skin and Connective Tissue Diseases |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Placebo drink | Dietary Supplement | consume 1 sachet per day |
|
| Change from Baseline L* value at 8 weeks |
| The change of skin moisture | Corneometer® CM825 was utilized to measure skin moisture. Units: arbitrary Corneometer® units 0-120 | Change from Baseline skin moisture at 8 weeks |
| The change of skin spots | VISIA Complexion Analysis System was utilized to measure skin spots. Units: arbitrary units | Change from Baseline skin spots at 8 weeks |
| The change of skin UV spots | VISIA Complexion Analysis System was utilized to measure skin UV spots. Units: arbitrary units | Change from Baseline skin UV spots at 8 weeks |
| The change of skin brown spots | VISIA Complexion Analysis System was utilized to measure skin brown spots. Units: arbitrary units | Change from Baseline skin brown spots at 8 weeks |
| The change of SOD-RBC of blood | Venous blood was sampled to measure SOD-RBC | Change from Baseline SOD-RBC at 8 weeks |
| The change of t-GSH of blood | Venous blood was sampled to measure t-GSH | Change from Baseline t-GSH at 8 weeks |
| The change of GST-RBC of blood | Venous blood was sampled to measure GST-RBC | Change from Baseline GST-RBC at 8 weeks |
| The change of blood total antioxidant capacity (TAC) | Venous blood was sampled to measure concentrations of TAC | Change from Baseline TAC at 8 weeks |
| The change of desmosine of blood | Venous blood was sampled to measure concentrations of desmosine | Change from Baseline desmosine at 8 weeks |
| The change of TNF-alpha of blood | Venous blood was sampled to measure concentrations of TNF-alpha | Change from Baseline TNF-alpha at 8 weeks |
| The change of transepidermal water loss (TEWL) | Tewameter® TM300 was utilized to measure TEWL. Units: g/hm² | Change from Baseline TEWL at 8 weeks |
Venous blood was sampled to measure renal function biomarkers
| Change from Baseline renal function biomarkers at 8 weeks |
| The change of self-assessment skin condition | A self-assessment questionnaire was collected to evaluate skin condition | Change from Baseline skin condition at 8 weeks |