Antithrombotic Activities of a Novel Yogurt Drink

Antithrombotic Activities of a Novel Yogurt Drink: a Dietary Intervention Study

This study aims to evaluate antithrombotic activities of novel yoghurt drink in healthy adult volunteers

This randomized controlled, double-blinded crossover study aims to investigate the antithrombotic activities of a novel yoghurt drink in healthy adult volunteers. It is anticipated that the novel drink containing beneficial polar lipids will reduce platelet aggregation in participants and consequently decrease the onset of cardiovascular disease.

In Phase I, the subjects will provide blood samples after overnight fasting and then take either a yoghurt drink (YD) or placebo (that does not contain polar lipids) daily for 4 weeks. Following this period, they will again provide blood samples. Then, after a 2-week washout period in which the subjects do not take any yoghurt or placebo drink , Phase II of the clinical trial will commence. This is the crossover phase in which subjects who took YD will now be given a placebo drink, and vice versa, over 4 weeks. A total of 80 blood samples will be collected for analysis.

Inclusion Criteria:

• Healthy adults

Exclusion Criteria:

• Volunteers need to be off medication and off any dietary supplements.
• Subjects must not have any blood clotting disorders or dyslipidaemia.
• Dairy intake needs to be within a normal range of 1-2 portions a week.
• Unwilling to follow the study requirements.