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The purpose of this study is to investigate the possible antioxidant and anti-inflammatory effects of yogurt enriched with polyphenols after 2-week consumption by healthy individuals.
Eighteen healthy adult volunteers of both sexes consumed yogurt (400g per day) enriched with polyphenols (10mg/100g yogurt) or yogurt (400g per day) not enriched with polyphenols for two weeks in a double-blind, crossover, randomized manner.There was a washout period of at least 10 days. Physiological data and blood samples were collected before and after consumption of each yogurt.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Yogurt enriched with polyphenols | Experimental | Two yogurts (400g) enriched with polyphenols (10mg/100g yogurt) per day, for two weeks. |
|
| Yogurt not enriched with polyphenols | Placebo Comparator | Two yogurts (400g) not enriched with polyphenols per day, for two weeks. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Yogurt enriched with polyphenols | Other | Yogurt enriched with polyphenols extracted from grape seeds |
|
| Measure | Description | Time Frame |
|---|---|---|
| Antioxidant effects | Indices of blood antioxidant status | Two weeks |
| Anti-inflammatory effects | Indices of inflammation in blood | Two weeks |
| Measure | Description | Time Frame |
|---|---|---|
| Body composition | Body fat percentage | Two weeks |
| Blood pressure | Blood pressure at rest | Two weeks |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Athanasios Z Jamurtas, PhD | University of Thessaly | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Department of Physical Education & Sport Science of the University of Thessaly | Trikala | Karyes | 42100 | Greece |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 24583382 | Background | Najgebauer-Lejko D, Grega T, Tabaszewska M. Yoghurts with addition of selected vegetables: acidity, antioxidant properties and sensory quality. Acta Sci Pol Technol Aliment. 2014 Jan-Mar;13(1):35-42. doi: 10.17306/j.afs.2014.1.3. | |
| 25154916 | Background | Lamothe S, Azimy N, Bazinet L, Couillard C, Britten M. Interaction of green tea polyphenols with dairy matrices in a simulated gastrointestinal environment. Food Funct. 2014 Oct;5(10):2621-31. doi: 10.1039/c4fo00203b. Epub 2014 Aug 26. |
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| ID | Term |
|---|---|
| D007249 | Inflammation |
| ID | Term |
|---|---|
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
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| ID | Term |
|---|---|
| D059808 | Polyphenols |
| ID | Term |
|---|---|
| D010636 | Phenols |
| D001555 | Benzene Derivatives |
| D006841 | Hydrocarbons, Aromatic |
| D006844 | Hydrocarbons, Cyclic |
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| Yogurt not enriched with polyphenols | Other | Yogurt not enriched with polyphenols |
|
| Hydration | Urine specific gravity | Two weeks |
| Resting heart rate | Resting heart rate | Two weeks |
| Blood glucose levels | Two weeks |
| Triglyceride levels | Two weeks |
| Total cholesterol levels | Two weeks |
| High Density Lipoprotein cholesterol levels | Two weeks |
| D006838 |
| Hydrocarbons |
| D009930 | Organic Chemicals |