Antithrombotic Activities of a Novel Yoghurt Drink: a Postprandial Study

Antithrombotic Activities of a Novel Yoghurt Drink: a Postprandial Study

The project aims to investigate the antithrombotic activity of the novel yoghurt drink enriched with polar lipids derived from ovine milk. The health claims the formulated novel or functional food on EFSA guidelines "The scientific requirements for health claims related to antioxidants, oxidative damage and cardiovascular health" and in a particular paragraph 5.4, "Claims on reduced platelet aggregation" "Platelet hyperactivity and hypercoagulability states are more commonly observed in subjects with cardiovascular (CV) risk factors. Healthy subjects or participants at very low risk of CV disease normally have non-activated circulating platelets. Reducing platelet aggregation in subjects with platelet activation during sustained exposure to the food/constituent (e.g., four weeks) would be a beneficial physiological effect".

Within this investigation, the postprandial effects of this novel yoghurt drink against platelet aggregation are going to be studied ex vivo in blood from healthy human subjects as described in previously established procedures.

Inclusion Criteria:

• • Healthy subjects need to have their dietary and dairy intake within the range [1-2 serves per week]

Exclusion Criteria:

• Subjects will be excluded from the study if they are

  • Under medication and intake of dietary supplements
  • Treatment for blood clotting disorders or dyslipidaemia