Lipid Encapsulation for Ileal Brake Activation

The Effect of Orally Applied Encapsulated Lipids in Yoghurt on Satiety and Food Intake: a Randomized Single-blind Placebo-controlled Study With Cross-over Design

This study evaluates the ability of encapsulation of orally applied lipids in a yoghurt snack to modify ad libitum food intake and satiety, without GI symptoms. Every subject receives two treatments (active, and placebo) on two different days, following a randomized cross-over design.

Inclusion Criteria:

• BMI between 25-30 kg/m2
• Voluntary participation

Exclusion Criteria:

• Milk (-protein or lactose)- allergy/intolerance
• History of serious GI complaints/surgeries
• Pregnancy, lactation
• Excessive alcohol consumption (>20 per week)
• Abnormal eating behaviour
• Intention to stop smoking
• Reported unexplained weight loss or gain in the month prior to screening
• Self-admitted HIV-positive state