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The main objective of the study is to evaluate the efficacy of a combined training program of physical exercise and multisensory stimulation (Physiocognitive Integration) in people with mild/moderate cognitive impairment.
Alzheimer's disease and other dementias are the main cause of cognitive impairment, with a prevalence of 0.4% worldwide and 1.23 in Europe. The WHO estimates that the growth of people with cognitive impairment to some degree will increase in the coming years, exceeding 75 million people in the world in 2030, and 135 million in 2050. The prevention of cognitive deterioration is mainly based on the implementation of non-pharmacological therapies. Multisensory stimulation is a non-pharmacological therapy that has benefits in patients with cognitive impairment, producing an improvement in cognitive function.
Physical exercise is associated with a lower risk of onset of cognitive impairment and less cognitive impairment as well as a slower progression in people with mild cognitive impairment and in mild-stage dementias. In addition to the cognitive sphere, the positive effect of physical exercise in preventing falls has been widely studied.
The main objective of the study is to evaluate the efficacy of a combined training program of physical exercise and multisensory stimulation (Physiocognitive Integration) in people with mild/moderate cognitive impairment. In order to do this, a experimental group will perform 20 sessions of multisensory training in addition to their current therapy and a second, control group, only their current therapy. Before and after the time need to complete the 20 sessions, all subjects were perform a battery of motor and cognitive tasks.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Intervention Group | Experimental | Subjects in the intervention group will perform 20 sessions of multisensory training |
|
| Control Group | Active Comparator | Subjects in the Control Group will not perform 20 sessions of multisensory training and they will keep doing the current therapy |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Cognitive therapy | Other | Cognitive therapy |
| |
| Measure | Description | Time Frame |
|---|---|---|
| Speed of Gait at preferred pace | Variables: Speed (m/s) | baseline |
| Speed of Gait at preferred pace | Variables: Speed (m/s) | at week 8 |
| Cadence of Gait at preferred pace | Variables: cadence (steps/min) | baseline |
| Cadence of Gait at preferred pace | Variables: cadence (steps/min) | at week 8 |
| Step Length of Gait at preferred pace | Variables: Step Length (m) | baseline |
| Step Length of Gait at preferred pace | Variables: Step Length (m) | at week 8 |
| Speed during Dual task gait | Variables: Speed (m/s) | baseline |
| Speed during Dual task gait | Variables: Speed (m/s) | at week 8 |
| Cadence during Dual task gait | Variables: cadence (steps/min) |
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Inclusion Criteria:
In the case of subjects who are part of the intervention group, the following will also be inclusion criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Universidad Rey Juan Carlos | Fuenlabrada | Madrid | 28942 | Spain |
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| ID | Term |
|---|---|
| D003704 | Dementia |
| D009043 | Motor Activity |
| ID | Term |
|---|---|
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
| D009422 | Nervous System Diseases |
| D019965 | Neurocognitive Disorders |
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| ID | Term |
|---|---|
| D015928 | Cognitive Behavioral Therapy |
| ID | Term |
|---|---|
| D001521 | Behavior Therapy |
| D011613 | Psychotherapy |
| D004191 | Behavioral Disciplines and Activities |
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| Physiocognitive Integration |
| Behavioral |
Physiocognitive Integration |
|
| Baseline |
| Cadence during Dual task gait | Variables: cadence (steps/min) | at week 8 |
| Step Length during Dual task gait | Variables: Step Length (m) | Baseline |
| Step Length during Dual task gait | Variables: Step Length (m) | at week 8 |
| Time up & go test | Variables: time (seconds) | baseline |
| Time up & go test | Variables: time (seconds) | at week 8 |
| D001523 | Mental Disorders |
| D001519 | Behavior |