The Effect of PCA on PONV After Microvascular Decompression

The Effect of Patient-controlled Analgesia (Ketorolac vs. Fentanyl) on the Development of Postoperative Nausea and Vomiting in Patients Undergoing Microvascular Decompression: a Prospective Randomized Controlled Trial

This study is a randomized, controlled, double-blinded, and parallel design study. A total 94 patients will be randomized to receive ketorolac or fentanyl based patient-controlled analgesia after microvascular decompression surgery.

Inclusion Criteria:

• Patients who undergo elective microvascular decompression surgery
• American Society of Anesthesiologists grade 1 or 2
• 19 - 65 years old

Exclusion Criteria:

• Refuse to participate to the study
• Refuse to use Patient-controlled analgesia
• Body Mass Index < 18.5 kg/m2 or > 35 kg/m2
• history of craniotomy or chemotheraphy
• Patients who used preoperative antiemetics within 24h before surgery
• Severe renal or hepatic dysfunction
• Pregnant