Nefopam as a Multimodal Analgesia for Thoracic Surgery

Nefopam as a Multimodal Analgesia for Video-assisted Thoracoscopic Surgery

Acute postoperative pain after video-assisted thoracoscopic surgery is very severe. Because pain after thoracic surgery prevents early recovery, and increases postoperative complications, its is important to prevent pain after video-assisted thoracoscopic surgery. In the present study, we will evaluate whether nefopam reduces pain after video-assisted thoracoscopic surgery.

Inclusion Criteria:

• patient scheduled for elective video-assisted thoracoscopic surgery
• American Society of Anesthesiologists physical grade I, II, III
• patient aged from 18 years old

Exclusion Criteria:

• history of allergy in nonsteroidal anti-inflammatory drugs, or nefopam
• renal insufficiency
• liver insufficiency
• myocardial infarction
• glaucoma
• pregnant and lactating women at the time of surgery
• patient who did not consent to the use of patient-controlled analgesia