Application of Circulating Exosomes in Early Diagnosis and Prognosis Evaluation After Intracerebral Hemorrhage

Application of Circulating Exosomes in Early Diagnosis and Prognosis Evaluation After Intracerebral Hemorrhage

The purpose of this study is to observe the relationship between the changes of circulating exosomes and the development and outcome of the disease in patients with intracerebral hemorrhage, and to search for early serum markers and potential intervention targets for disease monitoring in patients with intracerebral hemorrhage

Inclusion Criteria:

1. No systematic treatment was given before admission;
2. The patients were diagnosed with cerebral hemorrhage, and had imaging evidence;
3. The age was more than 18 years old;
4. The patient or family member agrees to sign the informed consent.

Exclusion Criteria:

1. Hematoma is caused by secondary factors (intracranial tumor, arteriovenous malformation or aneurysm);
2. Bleeding into the ventricle;
3. Multiple cerebral hemorrhage;
4. The patient did not receive treatment in our hospital;
5. Severe disability, dementia, or organ dysfunction before onset
6. Coagulopathy or long-term use of anticoagulants
7. Hematoma affects brain stem
8. Subjects refused to participate