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The investigators design a retrospective, observational cohort study to provide contemporary information on the prevalence, characteristics, risk stratification,cost-effective, treatments and prognosis of Chinese hospitalized adult patients with intracerebral hemorrhage.
Intracerebral hemorrhage (ICH) remains a devastating disease with high mortality, yet few therapeutic managements have been proved effective. Large quantities of work needs to be done to fully delineate the prevalence and prognosis of ICH. Hence, the investigators design a prospective, observational cohort study to provide contemporary information on the prevalence, characteristics, risk stratification,cost-effective, treatments and prognosis of Chinese hospitalised adult patients with ICH.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Second Affiliated Hospital, School of Medicine, Zhejiang University | a prospective cohort of patients of primary intracerebral hemorrhage in Second Affiliated Hospital, School of Medicine, Zhejiang University | ||
| Second People's Hospital of Hangzhou City, Zhejiang Province | a prospective cohort of patients of primary intracerebral hemorrhage in Second People's Hospital of Hangzhou City, Zhejiang Province | ||
| 4th Affiliated Hospital, School of Medicine at Zhejiang University | a prospective cohort of patients of primary intracerebral hemorrhage in 4th Affiliated Hospital, School of Medicine at Zhejiang University |
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| Measure | Description | Time Frame |
|---|---|---|
| proportion of patients with a 3-month modified Rankin Scale (mRS) score≤ 3 proportion of patients with a 3-month modified Rankin Scale (mRS) score≤ 3 proportion of patients with a 3-month modified Rankin Scale (mRS) score≤ 3 | mRS 0-6, higher indicate worse outcome | 2-3years |
| Measure | Description | Time Frame |
|---|---|---|
| Absolute peripheral hematoma edema(PHE) growth | absolute peripheral hematoma edema growth in CT/MRI measured by picture archiving and communication systems(PACS) system absolute peripheral hematoma edema growth in CT/MRI measured by PACS system | 2-3years |
| Relative peripheral hematoma edema(rPHE) |
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Inclusion Criteria:
Exclusion Criteria:
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Hospitalized patients over 18 years old with primary intrcerebral hemorrhage will be enrolled consecutively.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Feng Gao, MD,PhD | Contact | 13588451471 | 2202012@zju.edu.cn | |
| Lusha Tong, MD,PhD | Contact | 15868171218 |
| Name | Affiliation | Role |
|---|---|---|
| Feng Gao, MD,PhD | Second Affiliated Hospital, School of Medicine, Zhejiang University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| 2nd Affiliated Hospital, School of Medicine at Zhejiang University | Recruiting | Hangzhou | Zhejiang | 310000 | China |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 37949481 | Derived | Jin Y, Huang YH, Chen YP, Zhang YD, Li J, Yang KC, Ye X, Jin LH, Wu J, Yuan CZ, Gao F, Tong LS. Combined effect of cortical superficial siderosis and cerebral microbleed on short-term and long-term outcomes after intracerebral haemorrhage. Stroke Vasc Neurol. 2024 Aug 27;9(4):429-438. doi: 10.1136/svn-2023-002439. | |
| 37213900 | Derived |
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| ID | Term |
|---|---|
| D002543 | Cerebral Hemorrhage |
| D006973 | Hypertension |
| ID | Term |
|---|---|
| D020300 | Intracranial Hemorrhages |
| D002561 | Cerebrovascular Disorders |
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
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Peripheral blood
absolute PHE divided by hematoma volume in CT/MRI |
| 2-3years |
| National institute of health stroke scale(NIHSS score) | NIHSS 0-42, higher indicate worse outcome | 2-3years |
| Jin YJ, Li JW, Wu J, Huang YH, Yang KC, An HN, Yuan CZ, Gao F, Tong LS. Cortical superficial siderosis, hematoma volume, and outcomes after intracerebral hemorrhage: a mediation analysis. Front Neurol. 2023 May 5;14:1122744. doi: 10.3389/fneur.2023.1122744. eCollection 2023. |
| 36425320 | Derived | Li J, Shen D, Zhou Y, Jin Y, Jin L, Ye X, Tong L, Gao F. Underlying microangiopathy and functional outcome of simultaneous multiple intracerebral hemorrhage. Front Aging Neurosci. 2022 Nov 8;14:1000573. doi: 10.3389/fnagi.2022.1000573. eCollection 2022. |
| D009422 | Nervous System Diseases |
| D014652 | Vascular Diseases |
| D002318 | Cardiovascular Diseases |
| D006470 | Hemorrhage |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |