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The study aims to retrospectively investigate the endoscopic resection procedures of cancerous and precancerous lesions of the upper and lower digestive tract in order to evaluate the efficacy and safety outcomes and to compare different resection techniques. In particular, the resection techniques investigated will be mucosectomy, en bloc and piecemeal, endoscopic submucosal dissection (ESD) and its variants, full-thickness resection. The anatomical districts involved will be the esophagus, stomach, duodenum, colon and rectum.
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Endoscopic resection | Procedure | The endoscopic resection is the procedure that allows to remove cancerous or precancerous conditions of digestive tract. Endoscopic resection can be preformed by several techniques:
|
| Measure | Description | Time Frame |
|---|---|---|
| en bloc resection rate | the en bloc resection is the ability to remove the neoplasia in a single piece | one month |
| complete resection rate | the complete resection is the ability to remove the neoplasia with clear margins (R0) | one month |
| recurrence rate | recurrence is the recurrence of the neoplasm at the resection site during follow-up | one year |
| Measure | Description | Time Frame |
|---|---|---|
| adverse events rate | complication rate, early or late, related to the procedure used for endoscopic resection | one month |
| costs | evaluation of the costs incurred to perform the endoscopic resection |
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Inclusion Criteria:
Exclusion Criteria:
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Patients> 18 years of age who have undergone endoscopic resection of cancerous or pre-cancerous lesions of the digestive tract will be included in the study
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Paolo Cecinato, MD | Contact | +390522296111 | paolo.cecinato@ausl.re.it |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| IRCCS-AUSL Reggio Emilia | Recruiting | Reggio Emilia | RE | Italy |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 36542136 | Derived | Cecinato P, Lisotti A, Azzolini F, Lucarini M, Bassi F, Fusaroli P, Sassatelli R. Left colonic localization, non-granular morphology, and pit pattern independently predict submucosal fibrosis of naive colorectal neoplasms before endoscopic submucosal dissection. Surg Endosc. 2023 Apr;37(4):3037-3045. doi: 10.1007/s00464-022-09828-0. Epub 2022 Dec 21. |
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| ID | Term |
|---|---|
| D013274 | Stomach Neoplasms |
| D003110 | Colonic Neoplasms |
| D004938 | Esophageal Neoplasms |
| D004379 | Duodenal Neoplasms |
| ID | Term |
|---|---|
| D005770 | Gastrointestinal Neoplasms |
| D004067 | Digestive System Neoplasms |
| D009371 | Neoplasms by Site |
| D009369 | Neoplasms |
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| ID | Term |
|---|---|
| D000069916 | Endoscopic Mucosal Resection |
| ID | Term |
|---|---|
| D016099 | Endoscopy, Gastrointestinal |
| D016145 | Endoscopy, Digestive System |
| D003938 | Diagnostic Techniques, Digestive System |
| D019937 | Diagnostic Techniques and Procedures |
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| one month |
| D004066 |
| Digestive System Diseases |
| D005767 | Gastrointestinal Diseases |
| D013272 | Stomach Diseases |
| D015179 | Colorectal Neoplasms |
| D007414 | Intestinal Neoplasms |
| D003108 | Colonic Diseases |
| D007410 | Intestinal Diseases |
| D006258 | Head and Neck Neoplasms |
| D004935 | Esophageal Diseases |
| D004378 | Duodenal Diseases |
| D003933 | Diagnosis |
| D004724 | Endoscopy |
| D003949 | Diagnostic Techniques, Surgical |
| D013505 | Digestive System Surgical Procedures |
| D013514 | Surgical Procedures, Operative |
| D019060 | Minimally Invasive Surgical Procedures |