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To evaluate clinical outcome for patients receiving treatment of suspected premalignant and malignant gastrointestinal lesions at Interventional Endoscopy Services. The primary outcome is curative endoscopic resection. Secondary outcomes include resection technique utilized, rates of en bloc resection and adverse event rates, including infection, bleeding, perforation and death, and one-year survival rates.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Mucosal tumors of the colon | Patients who received endoscopic treatment for noninvasive mucosal tumors of the colon. | ||
| Nonampullary tumors of the duodenum | Patients who received endoscopic treatment for noninvasive mucosal tumors of the duodenum. | ||
| Ampullary tumors | Patients who received endoscopic treatment for noninvasive ampullary tumors. |
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| Measure | Description | Time Frame |
|---|---|---|
| Technical success. | Technical success is defined as complete resection confirmed by the endoscopic absence of adenomatous tissue after inspection with high-definition white light and narrow-band imaging. | 1 day to 3 months |
| Measure | Description | Time Frame |
|---|---|---|
| Short term recurrence rate | Freedom from recurrence on follow-up endoscopy with high definition white light and narrow band imaging and on mucosal biopsies of the endoscopic mucosal resection site | Less than 1 year |
| Long term recurrence rate |
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Inclusion Criteria:
Exclusion Criteria:
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Patients referred to Interventional Endoscopy Services at CPMC for treatment of GI tract tumors.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Jona C Bernabe | Contact | 415-600-1151 | jona.bernabe@sutterhealth.org | |
| Hayden Sampson | Contact | 415-600-1151 | Hayden.sampson@sutterhealth.org |
| Name | Affiliation | Role |
|---|---|---|
| Kenneth F Binmoeller, M.D. | California Pacific Medical Center | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Interventional Endoscopy Services | Recruiting | San Francisco | California | 94115 | United States |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 26375437 | Derived | Binmoeller KF, Hamerski CM, Shah JN, Bhat YM, Kane SD. Underwater EMR of adenomas of the appendiceal orifice (with video). Gastrointest Endosc. 2016 Mar;83(3):638-42. doi: 10.1016/j.gie.2015.08.079. Epub 2015 Sep 14. | |
| 25708759 | Derived | Binmoeller KF, Hamerski CM, Shah JN, Bhat YM, Kane SD, Garcia-Kennedy R. Attempted underwater en bloc resection for large (2-4 cm) colorectal laterally spreading tumors (with video). Gastrointest Endosc. 2015 Mar;81(3):713-8. doi: 10.1016/j.gie.2014.10.044. |
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| ID | Term |
|---|---|
| D005770 | Gastrointestinal Neoplasms |
| ID | Term |
|---|---|
| D004067 | Digestive System Neoplasms |
| D009371 | Neoplasms by Site |
| D009369 | Neoplasms |
| D004066 | Digestive System Diseases |
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Freedom from recurrence on follow-up endoscopy with high definition white light and narrow band imaging and on mucosal biopsies of the endoscopic mucosal resection site
| Greater than 1 year |
| Adverse event rate | Adverse events include infection, bleeding, perforation and death. | up to 1 month post procedure. |
| Endoscopic en bloc resection rate | Resection in 1 piece without fragmentation, along or extrinsic to the diathermic markings placed around the perimeter of the lesion before resection, without remnant abnormal tissue visible on HD white-light imaging or NBI | Immediate |
| D005767 |
| Gastrointestinal Diseases |