An observational, prospective, multicentre and international study. This will be a non-interventional study to evaluate the efficacy and safety of endoscopic resection of gastrointestinal lesions and to determine what are the factors related to complications, and to describe these lesions according to the different morphologic and histologic classifications.

Inclusion Criteria:

• Female and male patients who are at least 18 years old.
• Clinical indication for endoscopic exam and endoscopic resection
• Patients must freely accept their involvement in this study. They shall give a written informed consent

Exclusion Criteria:

• Patients who do not desire to be included in this study

Patients with a clinical indication for endoscopic resection at the different participating centers will be consecutively included in this study.