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In a former study, four vanilloid compounds were observed increased in the urin of autistic patients. The present study is aimed at performing a ambispective study to confirm or not these preliminary results. 70 urins from autistic children (already collected) will be compared to 70 urins of non autistic children (collected without intervention, remaining sample from the standard care), in terms of measurements of four vanilloid compounds using a GCMS apparatus.
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| Measure | Description | Time Frame |
|---|---|---|
| measurements of vanilloid compound in urins | The primary end point is to determine if isolated or combinations of vanilloid compound measured in urin, may discriminate autistic vs non autistic childen | through study completion, an average of 18 months |
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Inclusion criteria :
For cases :
For healthy chlidren:
Exclusion criteria
For cases:
For healthy chlidren :
only males will be studied
Autistic children according to CM-10 (F84.0)
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Marc Merten, PhD | Contact | 33 616 364 916 | m.merten@chru-nancy.fr | |
| Jean-Luc Olivier, MD, PhD, Pr | Contact | jl.olivier@chru-nancy.fr |
| Name | Affiliation | Role |
|---|---|---|
| Jean-Luc Olivier, MD, PhD, | CHRU Nancy | Study Director |
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| ID | Term |
|---|---|
| D000067877 | Autism Spectrum Disorder |
| ID | Term |
|---|---|
| D002659 | Child Development Disorders, Pervasive |
| D065886 | Neurodevelopmental Disorders |
| D001523 | Mental Disorders |
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urines