Not provided
| ID | Type | Description | Link |
|---|---|---|---|
| 2009-011842-24 | EudraCT Number |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Class |
|---|---|
| Henri Mondor University Hospital | OTHER |
| Albert Chenevier Hospital (Department of Psychiatry) | UNKNOWN |
| Hopital Universitaire Robert-Debre | OTHER |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Autism spectrum disorders (ASDs) are complex neurodevelopmental conditions characterized by deficits in social communication, delay in language and repetitive behaviors. Results from genetic studies reveal one pathway associated with susceptibility to ASDs, which includes synaptic cell adhesion molecules. Among the factors that could modulate this pathway are the genes controlling circadian rhythms. Sleep disorders and low melatonin levels are frequently observed in ASDs. Thus investigator will characterize the circadian rhythms of patients with ASD and search for circadian rhythms genes polymorphisms.
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Autistic Patient | Other |
|
|
| Controls | Other |
|
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Autistic functional exploration | Other |
|
| Measure | Description | Time Frame |
|---|---|---|
| Urinary sulfatoxymelatonin secretion | The determination will be performed at 14 days ( child) | |
| Urinary sulfatoxymelatonin secretion | The determination will be performed at 21 days ( adults) |
| Measure | Description | Time Frame |
|---|---|---|
| Core body temperature rhythm | The determination will be performed at 5 days (adult) | |
| Circadian rhythms assessed with actometer | The determination will be performed at 14 ( child) and 21 days (adult) |
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Affiliation | Role |
|---|---|---|
| Xavier DROUOT, MCU-PH | Assistance Publique - Hôpitaux de Paris | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Henri Mondor Hospital | Créteil | 94000 | France |
Not provided
| ID | Term |
|---|---|
| D001321 | Autistic Disorder |
| ID | Term |
|---|---|
| D000067877 | Autism Spectrum Disorder |
| D002659 | Child Development Disorders, Pervasive |
| D065886 | Neurodevelopmental Disorders |
| D001523 | Mental Disorders |
Not provided
Not provided
| Pasteur Institute (Cognitive Function and Human Genetic) |
| UNKNOWN |
| Fondation FondaMental | OTHER |
Not provided
Not provided
Not provided
Not provided
Not provided
| Control functional exploration | Other |
|
|