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This study examines the effect of soluble fiber dextrin on food intake, appetite, and physiological markers of appetite. Adults aged 18-45 years with a BMI were recruited for this study. Participants were given two doses of SFD in the morning and appetite, food intake and physiological markers of appetite were measured over 10 years.
Overweight and obesity are leading health problems. The study investigates the effect of a food ingredient from two different sources at two different doses on food intake and appetite markers over a 10 hour period. All participants reported to the laboratory first thing in the morning and remained in the laboratory until after their evening meal. A fixed breakfast was served but the participants were free to eat as much as they liked at lunch and dinner. Blood was taken at regular intervals during the day and assayed for glucose and several hormones related to appetite. Subjective measures of appetite were also collected over the 10 hour test session.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| SFD Tapioca 20g | Experimental | 20g soluble fiber dextrin derived from tapioca |
|
| SFD Tapioca 40g | Experimental | 40g soluble fiber dextrin derived from tapioca |
|
| SFD corn 20g | Experimental | 40g soluble fiber dextrin derived from corn |
|
| SFD corn 40g | Experimental |
| |
| Control | Placebo Comparator | Maltodextrin |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Soluble Fiber Dextrin | Other | Ingredient based on resistant starch |
|
| Measure | Description | Time Frame |
|---|---|---|
| Food intake | Food intake measured at lunch and evening meal. | 10 hours |
| Measure | Description | Time Frame |
|---|---|---|
| Appetite | Subjective appetite measures using questionnaires at regular intervals over 10 hours, | 10 hours |
| CCK | Plasma CCK measured at regular intervals over 10 hours. |
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Inclusion Criteria:
BMI 19.9 - 29.9 Aged 18-45 Find the study foods to be palatable
Exclusion Criteria:
Weight change > 3kg in the past three months Do not regularly consume snacks Presence or history of GI disorders Restrained eater Used medication that influences appetite
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| ID | Term |
|---|---|
| D001070 | Appetitive Behavior |
| ID | Term |
|---|---|
| D001522 | Behavior, Animal |
| D001519 | Behavior |
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Human subjects
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Material was provided in coded plain packaging. Participants and researchers were unaware of what was being received.
| 10 hours |
| GLP-1 | Plasma GLP-1 measured at regular intervals over 10 hours. | 10 hours |
| PYY3-36 | Plasma PYY3-36 measured at regular intervals over 10 hours. | 10 hours |
| Breath Hydrogen | Breath hydrogen measured at regular intervals over 10 hours. | 10 hours |