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| Name | Class |
|---|---|
| Tate and Lyle Ingredients France | INDUSTRY |
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Research suggests dietary fiber may play a role in weight management, and fiber consumption is inversely associated with body weight, body fat, and BMI in cross-sectional studies. These effects may be mediated by increased satiety, reduced food intake, or changes in blood levels of glucose, insulin, and gut hormones.
The purpose of this study is to determine the satiety, glycemic, hormonal, and gastrointestinal responses of novel fiber supplements.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| No fiber | Placebo Comparator | No fiber added to study products |
|
| Resistant Starch | Experimental | Muffins, cereal, and bars made with a resistant starch |
|
| Resistant starch + soluble fiber | Experimental | Muffins, cereal, and bars made with a mixture of resistant starch and a soluble fiber |
|
| Fiber made from corn starch | Experimental | Muffins, cereal, and bars made with novel corn fiber |
|
| Fiber made from corn starch + soluble fiber | Experimental | Muffins, cereal, and bars made with a mixture of novel corn fiber and a soluble fiber |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Placebo | Dietary Supplement | Low fiber muffin, hot cereal and beverage (acute phase) or fiber bars and beverage (chronic phase) |
|
| Measure | Description | Time Frame |
|---|---|---|
| Satiety | 0, 15, 30, 45, 60, 90, 120, 180, 215 minutes postprandially |
| Measure | Description | Time Frame |
|---|---|---|
| ad libitum food intake | 180 minutes postprandially and over 24 hours | |
| Ghrelin, polypeptide YY (PYY), and glucagon-like peptide-1 (GLP-1) response | 0, 30, 60 minutes postprandially | |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Joanne L Slavin, PhD | University of Minnesota | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University of Minnesota - General Clinical Research Center | Minneapolis | Minnesota | 55455 | United States |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 23427334 | Derived | Timm DA, Thomas W, Boileau TW, Williamson-Hughes PS, Slavin JL. Polydextrose and soluble corn fiber increase five-day fecal wet weight in healthy men and women. J Nutr. 2013 Apr;143(4):473-8. doi: 10.3945/jn.112.170118. Epub 2013 Feb 20. |
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| ID | Term |
|---|---|
| D000084922 | Resistant Starch |
| ID | Term |
|---|---|
| D013213 | Starch |
| D005936 | Glucans |
| D001704 | Biopolymers |
| D011108 | Polymers |
| D046911 |
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| Resistant Starch | Dietary Supplement | 25 g resistant starch, administered in a muffin, hot cereal and beverage (acute phase) or fiber bars and beverage (chronic phase) |
|
| Resistant starch + soluble fiber | Dietary Supplement | 25 g fiber as resistant starch and a soluble fiber, administered in a muffin, hot cereal and beverage (acute phase) or fiber bars and beverage (chronic phase) |
|
| Fiber made from corn starch | Dietary Supplement | 25 g fiber made from corn starch, administered in a muffin, hot cereal and beverage (acute phase) or fiber bars and beverage (chronic phase) |
|
| Fiber made from corn starch + soluble fiber | Dietary Supplement | 25 g fiber as a fiber made from corn starch and a soluble fiber, administered in a muffin, hot cereal and beverage (acute phase) or fiber bars and beverage (chronic phase) |
|
| Gastrointestinal tolerance and fecal chemistry |
| following 7 days of treatment |
| Glucose/Insulin Response | 0, 15, 30, 45, 60, 90, 120, 180 minutes postprandially |
| Macromolecular Substances |
| D004043 | Dietary Fiber |
| D004040 | Dietary Carbohydrates |
| D002241 | Carbohydrates |
| D011134 | Polysaccharides |
| D005502 | Food |
| D000066888 | Diet, Food, and Nutrition |
| D010829 | Physiological Phenomena |
| D019602 | Food and Beverages |